# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3692450 | BDBM158621 | F | = | 140 | % | ALA4052967 | % | Canis lupus familiaris | |||
2. | ALA3692450 | BDBM158621 | Vd | = | 1.1 | L/Kg | ALA4052966 | L.kg-1 | Canis lupus familiaris | |||
3. | ALA3692450 | BDBM158621 | CL | = | 7 | ml/min.kg | ALA4052965 | mL.min-1.kg-1 | Canis lupus familiaris | |||
4. | ALA3692450 | BDBM158621 | Vd | = | 0.9 | L/Kg | ALA4052964 | L.kg-1 | Macaca fascicularis | |||
5. | ALA3692450 | BDBM158621 | CL | = | 21 | ml/min.kg | ALA4052963 | mL.min-1.kg-1 | Macaca fascicularis | |||
6. | ALA3692450 | BDBM158621 | F | = | 51 | % | ALA4052962 | % | Rattus norvegicus | |||
7. | ALA3692450 | BDBM158621 | Vd | = | 1.4 | L/Kg | ALA4052961 | L.kg-1 | Rattus norvegicus | |||
8. | ALA3692450 | BDBM158621 | CL | = | 7 | ml/min.kg | ALA4052960 | mL.min-1.kg-1 | Rattus norvegicus | |||
9. | ALA3692450 | BDBM158621 | PPB | = | 94 | % | ALA4052959 | % | Homo sapiens | |||
10. | ALA3692450 | BDBM158621 | CLH | = | 29 | ml/min.kg | ALA4052958 | mL.min-1.kg-1 | ||||
11. | ALA3692450 | BDBM158621 | CLH | = | 10 | ml/min.kg | ALA4052957 | mL.min-1.kg-1 | Canis lupus familiaris | |||
12. | ALA3692450 | BDBM158621 | CLH | = | 25 | ml/min.kg | ALA4052956 | mL.min-1.kg-1 | Mus musculus | |||
13. | ALA3692450 | BDBM158621 | CLH | = | 6 | ml/min.kg | ALA4052955 | mL.min-1.kg-1 | Rattus norvegicus | |||
14. | ALA3692450 | BDBM158621 | CLH | = | 7 | ml/min.kg | ALA4052954 | mL.min-1.kg-1 | Homo sapiens | |||
15. | ALA3692450 | BDBM158621 | Therm_solubility | = | 9 | ug ml-1 | ALA4052953 | ug.mL-1 | ||||
16. | ALA3692450 | BDBM158621 | Papp | = | 7.5 | ucm/s | ALA4052952 | ucm/s | ||||
17. | ALA3692450 | BDBM158621 | INH | > | 80 | % | ALA4052951 | % | Homo sapiens | |||
18. | ALA3692450 | BDBM158621 | Ki | > | 1000 | nM | ALA4052947 | nM | Homo sapiens | |||
19. | ALA3692450 | BDBM158621 | IC50 | > | 20 | uM | ALA4052941 | nM | Homo sapiens | |||
20. | ALA3692450 | BDBM158621 | IC50 | = | 67 | nM | ALA4052946 | 7.17 | nM | Homo sapiens |