# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3696476 | BDBM155922 | IC50 | = | 12 | nM | ALA3705774 | 7.92 | 298298 | nM | Rattus norvegicus | |
2. | ALA3696476 | BDBM155922 | F | = | 45 | % | ALA4427495 | % | ||||
3. | ALA3696476 | BDBM155922 | t1/2 | = | 0.86 | hr | ALA4427494 | hr | ||||
4. | ALA3696476 | BDBM155922 | AUC/dose | = | 0.13 | uM.hr.kg/mg | ALA4427493 | uM.hr.kg/mg | ||||
5. | ALA3696476 | BDBM155922 | Vdss | = | 5.8 | L/Kg | ALA4427492 | L.kg-1 | ||||
6. | ALA3696476 | BDBM155922 | CL | = | 82 | ml/min.kg | ALA4427491 | mL.min-1.kg-1 | ||||
7. | ALA3696476 | BDBM155922 | FC | = | 1 | ALA4427485 | Rattus norvegicus | |||||
8. | ALA3696476 | BDBM155922 | FC | = | 1.1 | ALA4427484 | Rattus norvegicus | |||||
9. | ALA3696476 | BDBM155922 | FC | = | 0.9 | ALA4427482 | Rattus norvegicus | |||||
10. | ALA3696476 | BDBM155922 | FC | = | 1.5 | ALA4427481 | Rattus norvegicus | |||||
11. | ALA3696476 | BDBM155922 | FC | = | 1.4 | ALA4427480 | Rattus norvegicus | |||||
12. | ALA3696476 | BDBM155922 | FC | = | 1.6 | ALA4427479 | Rattus norvegicus | |||||
13. | ALA3696476 | BDBM155922 | FC | = | 1.3 | ALA4427478 | Rattus norvegicus | |||||
14. | ALA3696476 | BDBM155922 | FC | = | 2.2 | ALA4427476 | Rattus norvegicus | |||||
15. | ALA3696476 | BDBM155922 | FC | = | 1.9 | ALA4427474 | Rattus norvegicus | |||||
16. | ALA3696476 | BDBM155922 | IC50 | = | 0.059 | uM | ALA4427473 | 7.23 | nM | Homo sapiens | ||
17. | ALA3696476 | BDBM155922 | IC50 | = | 0.134 | uM | ALA4427467 | 6.87 | nM | Homo sapiens | ||
18. | ALA3696476 | BDBM155922 | IC50 | = | 47 | uM | ALA4427468 | 4.33 | nM | Homo sapiens | ||
19. | ALA3696476 | BDBM155922 | IC50 | = | 0.012 | uM | ALA4427470 | 7.92 | nM | Homo sapiens | ||
20. | ALA3696476 | BDBM155922 | IC50 | = | 22 | uM | ALA4427471 | 4.66 | nM | Homo sapiens |