# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3696477 | BDBM155923 | IC50 | = | 10 | nM | ALA3705774 | 8.00 | 298299 | nM | Rattus norvegicus | |
2. | ALA3696477 | BDBM155923 | F | = | 44 | % | ALA4427495 | % | ||||
3. | ALA3696477 | BDBM155923 | t1/2 | = | 1.4 | hr | ALA4427494 | hr | ||||
4. | ALA3696477 | BDBM155923 | AUC/dose | = | 0.3 | uM.hr.kg/mg | ALA4427493 | uM.hr.kg/mg | ||||
5. | ALA3696477 | BDBM155923 | Vdss | = | 4.5 | L/Kg | ALA4427492 | L.kg-1 | ||||
6. | ALA3696477 | BDBM155923 | CL | = | 54 | ml/min.kg | ALA4427491 | mL.min-1.kg-1 | ||||
7. | ALA3696477 | BDBM155923 | FC | = | 1.3 | ALA4427485 | Rattus norvegicus | |||||
8. | ALA3696477 | BDBM155923 | FC | = | 1.1 | ALA4427482 | Rattus norvegicus | |||||
9. | ALA3696477 | BDBM155923 | FC | = | 3.7 | ALA4427481 | Rattus norvegicus | |||||
10. | ALA3696477 | BDBM155923 | FC | = | 3.5 | ALA4427479 | Rattus norvegicus | |||||
11. | ALA3696477 | BDBM155923 | FC | = | 4.1 | ALA4427476 | Rattus norvegicus | |||||
12. | ALA3696477 | BDBM155923 | FC | = | 4.5 | ALA4427474 | Rattus norvegicus | |||||
13. | ALA3696477 | BDBM155923 | IC50 | = | 0.01 | uM | ALA4427473 | 8.00 | nM | Homo sapiens | ||
14. | ALA3696477 | BDBM155923 | IC50 | = | 0.112 | uM | ALA4427467 | 6.95 | nM | Homo sapiens | ||
15. | ALA3696477 | BDBM155923 | IC50 | = | 100 | uM | ALA4427468 | 4.00 | nM | Homo sapiens | ||
16. | ALA3696477 | BDBM155923 | IC50 | = | 0.009 | uM | ALA4427470 | 8.05 | nM | Homo sapiens | ||
17. | ALA3696477 | BDBM155923 | IC50 | > | 30 | uM | ALA4427471 | nM | Homo sapiens | |||
18. | ALA3696477 | BDBM155923 | Ratio IC50 | > | 3000 | ALA4427472 |