# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3736012 | 10 | F | = | 92 | % | ALA3736605 | % | Mus musculus | |||
2. | ALA3736012 | 10 | AUClast | = | 27 | ug.hr/ml | ALA3736604 | ng.hr.mL-1 | Mus musculus | |||
3. | ALA3736012 | 10 | Cmax | = | 14 | ug ml-1 | ALA3736603 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
4. | ALA3736012 | 10 | Tmax | = | 0.25 | hr | ALA3736602 | hr | Mus musculus | |||
5. | ALA3736012 | 10 | F | = | 49 | % | ALA3739086 | % | Mus musculus | |||
6. | ALA3736012 | 10 | AUClast | = | 1.4 | ug.hr/ml | ALA3739085 | ng.hr.mL-1 | Mus musculus | |||
7. | ALA3736012 | 10 | Cmax | = | 1.6 | ug ml-1 | ALA3739084 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
8. | ALA3736012 | 10 | Tmax | = | 0.25 | hr | ALA3739083 | hr | Mus musculus | |||
9. | ALA3736012 | 10 | Vdss | = | 1.5 | L/Kg | ALA3739082 | L.kg-1 | Mus musculus | |||
10. | ALA3736012 | 10 | CL | = | 28 | ml/min.kg | ALA3739081 | mL.min-1.kg-1 | Mus musculus | |||
11. | ALA3736012 | 10 | AUClast | = | 0.6 | ug.hr/ml | ALA3739080 | ng.hr.mL-1 | Mus musculus | |||
12. | ALA3736012 | 10 | INH | 0 | ALA3739079 | Dose-dependent effect | % | Homo sapiens | ||||
13. | ALA3736012 | 10 | INH | 0 | ALA3739078 | Dose-dependent effect | % | Homo sapiens | ||||
14. | ALA3736012 | 10 | INH | 0 | ALA3739077 | Dose-dependent effect | % | Homo sapiens | ||||
15. | ALA3736012 | 10 | INH | 0 | ALA3739076 | Dose-dependent effect | % | Homo sapiens | ||||
16. | ALA3736012 | 10 | permeability | = | 26 | 10'-6/s | ALA3739075 | 10'-6/s | ||||
17. | ALA3736012 | 10 | solubility | = | 143 | ug ml-1 | ALA3739074 | ug.mL-1 | ||||
18. | ALA3736012 | 10 | solubility | = | 50 | ug ml-1 | ALA3739073 | ug.mL-1 | ||||
19. | ALA3736012 | 10 | CL | = | 25 | ml/min.kg | ALA3739072 | mL.min-1.kg-1 | Rattus norvegicus | |||
20. | ALA3736012 | 10 | Kinetic_solubility | = | 4 | ug ml-1 | ALA3739070 | ug.mL-1 |