# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3735648 | 15b | Activity | 0 | ALA3738665 | Non-toxic | Mus musculus | |||||
2. | ALA3735648 | 15b | Activity | 0 | ALA3738662 | Toxic | Mus musculus | |||||
3. | ALA3735648 | 15b | T/C | = | 0 | % | ALA3738658 | % | ||||
4. | ALA3735648 | 15b | F | = | 67.1 | % | ALA3738505 | % | Rattus norvegicus | |||
5. | ALA3735648 | 15b | AUC | = | 7286 | ng.hr/ml | ALA3738504 | ng.hr.mL-1 | Rattus norvegicus | |||
6. | ALA3735648 | 15b | Tmax | = | 4.5 | hr | ALA3738503 | hr | Rattus norvegicus | |||
7. | ALA3735648 | 15b | Cmax | = | 351 | ng/ml | ALA3738502 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
8. | ALA3735648 | 15b | t1/2 | = | 15.78 | hr | ALA3738498 | hr | Rattus norvegicus | |||
9. | ALA3735648 | 15b | Vdss | = | 17.36 | L/Kg | ALA3738497 | L.kg-1 | Rattus norvegicus | |||
10. | ALA3735648 | 15b | CL | = | 0.85 | L/hr/kg | ALA3738496 | mL.min-1.kg-1 | Rattus norvegicus | |||
11. | ALA3735648 | 15b | IC50 | = | 17.9 | nM | ALA3738495 | 7.75 | nM | |||
12. | ALA3735648 | 15b | IC50 | = | 3.9 | nM | ALA3738494 | 8.41 | nM | Homo sapiens | ||
13. | ALA3735648 | 15b | IC50 | = | 3.4 | nM | ALA3738493 | 8.47 | nM | Homo sapiens | ||
14. | ALA3735648 | 15b | IC50 | = | 2.65 | uM | ALA3864901 | 5.58 | nM | Homo sapiens | ||
15. | ALA3735648 | 15b | IC50 | = | 43.6 | nM | ALA3831014 | 7.36 | nM | Homo sapiens | ||
16. | ALA3735648 | 15b | Activity | 0 | ALA3831028 | Non-toxic | Mus musculus | |||||
17. | ALA3735648 | 15b | Activity | 0 | ALA3831025 | Active | ||||||
18. | ALA3735648 | 15b | Activity | 0 | ALA3831024 | Active | ||||||
19. | ALA3735648 | 15b | Activity | 0 | ALA3831023 | Active | ||||||
20. | ALA3735648 | 15b | Activity | 0 | ALA3831022 | Active |