| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3740897 | 14f; AZ0108 | F | = | 81 | % | ALA3860800 | % | ||||
| 2. | ALA3740897 | 14f; AZ0108 | CL | = | 0.9 | ml/min.Kg | ALA3860799 | mL.min-1.kg-1 | ||||
| 3. | ALA3740897 | 14f; AZ0108 | F | = | 79 | % | ALA3860796 | % | ||||
| 4. | ALA3740897 | 14f; AZ0108 | CL | = | 17 | ml/min.Kg | ALA3860795 | mL.min-1.kg-1 | ||||
| 5. | ALA3740897 | 14f; AZ0108 | Ratio | = | 2 | ALA3860794 | ||||||
| 6. | ALA3740897 | 14f; AZ0108 | Papp | = | 15.6 | 10'-6 cm/s | ALA3860793 | 10'-6 cm/s | ||||
| 7. | ALA3740897 | 14f; AZ0108 | EC50 | = | 0.053 | uM | ALA3860792 | 7.28 | nM | |||
| 8. | ALA3740897 | 14f; AZ0108 | EC50 | = | 30 | nM | ALA3745013 | 7.52 | nM | Homo sapiens | ||
| 9. | ALA3740897 | 14f; AZ0108 | EC50 | = | 30 | nM | ALA3745012 | 7.52 | nM | Homo sapiens | ||
| 10. | ALA3740897 | 14f; AZ0108 | EC50 | = | 123 | nM | ALA3743857 | 6.91 | nM | Homo sapiens | ||
| 11. | ALA3740897 | 14f; AZ0108 | Ratio IC50 | = | 100 | ALA3743856 | ||||||
| 12. | ALA3740897 | 14f; AZ0108 | Ratio IC50 | = | 100 | ALA3743855 | ||||||
| 13. | ALA3740897 | 14f; AZ0108 | Ratio IC50 | = | 100 | ALA3743854 | ||||||
| 14. | ALA3740897 | 14f; AZ0108 | IC50 | = | 0.083 | uM | ALA3743853 | 7.08 | nM | Homo sapiens | ||
| 15. | ALA3740897 | 14f; AZ0108 | Ratio IC50 | = | 100 | ALA3743852 | ||||||
| 16. | ALA3740897 | 14f; AZ0108 | Ratio IC50 | = | 100 | ALA3743851 | ||||||
| 17. | ALA3740897 | 14f; AZ0108 | Ratio IC50 | = | 100 | ALA3743850 | ||||||
| 18. | ALA3740897 | 14f; AZ0108 | GI50 | = | 0.017 | uM | ALA3743849 | nM | ||||
| 19. | ALA3740897 | 14f; AZ0108 | IC50 | > | 3 | uM | ALA3743848 | nM | Homo sapiens | |||
| 20. | ALA3740897 | 14f; AZ0108 | F | = | 81 | % | ALA3743846 | % | Canis lupus familiaris |
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