# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3758457 | 5a | AUClast | = | 3.01 | mg.hr/L | ALA3760281 | ng.hr.mL-1 | Mus musculus | |||
2. | ALA3758457 | 5a | t1/2 | = | 0.7 | hr | ALA3760272 | hr | Mus musculus | |||
3. | ALA3758457 | 5a | Cmax | = | 4.39 | mg/L | ALA3760269 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
4. | ALA3758457 | 5a | Tmax | = | 0.5 | hr | ALA3760266 | hr | Mus musculus | |||
5. | ALA3758457 | 5a | %max | = | 10.2 | % | ALA3760302 | % | Mus musculus | |||
6. | ALA3758457 | 5a | Ratio | = | 17 | ALA3760304 | ||||||
7. | ALA3758457 | 5a | Ratio | = | 5 | ALA3760303 | ||||||
8. | ALA3758457 | 5a | Activity | 0 | ALA3760301 | Non-toxic | Mus musculus | |||||
9. | ALA3758457 | 5a | TGI | = | 41 | % | ALA3760300 | % | Homo sapiens | |||
10. | ALA3758457 | 5a | TGI | = | 47 | % | ALA3760299 | % | Homo sapiens | |||
11. | ALA3758457 | 5a | TGI | = | 53 | % | ALA3760298 | % | Homo sapiens | |||
12. | ALA3758457 | 5a | IC50 | = | 37 | uM | ALA3760297 | 4.43 | nM | Homo sapiens | ||
13. | ALA3758457 | 5a | IC50 | = | 42 | nM | ALA3760296 | 7.38 | nM | Homo sapiens | ||
14. | ALA3758457 | 5a | IC50 | = | 927 | nM | ALA3760295 | 6.03 | nM | Homo sapiens | ||
15. | ALA3758457 | 5a | IC50 | = | 9.3 | uM | ALA3760294 | 5.03 | nM | Homo sapiens | ||
16. | ALA3758457 | 5a | IC50 | = | 1.5 | uM | ALA3760293 | 5.82 | nM | Homo sapiens | ||
17. | ALA3758457 | 5a | IC50 | = | 27 | nM | ALA3760292 | 7.57 | nM | Homo sapiens | ||
18. | ALA3758457 | 5a | IC50 | = | 354 | nM | ALA3760291 | 6.45 | nM | Homo sapiens | ||
19. | ALA3758457 | 5a | IC50 | = | 319 | nM | ALA3760290 | 6.50 | nM | Homo sapiens | ||
20. | ALA3758457 | 5a | IC50 | = | 25 | nM | ALA3760289 | 7.60 | nM | Homo sapiens |