# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3764300 | 20 | Activity | 0 | ALA3768624 | Non-toxic | Mus musculus | |||||
2. | ALA3764300 | 20 | Activity | 0 | ALA3768623 | Non-toxic | Mus musculus | |||||
3. | ALA3764300 | 20 | Activity | 0 | ALA3768622 | Non-toxic | Mus musculus | |||||
4. | ALA3764300 | 20 | Activity | 0 | ALA3768599 | Active | Homo sapiens | |||||
5. | ALA3764300 | 20 | INH | 0 | ALA3768597 | Dose-dependent effect | % | Homo sapiens | ||||
6. | ALA3764300 | 20 | INH | 0 | ALA3768596 | Dose-dependent effect | % | Homo sapiens | ||||
7. | ALA3764300 | 20 | IC50 | = | 2.3 | uM | ALA3768359 | 5.64 | nM | Homo sapiens | ||
8. | ALA3764300 | 20 | solubility | = | 30 | uM | ALA3768360 | nM | ||||
9. | ALA3764300 | 20 | EC50 | > | 27 | uM | ALA3768361 | nM | Homo sapiens | |||
10. | ALA3764300 | 20 | permeability | = | 16.6 | ucm/s | ALA3768362 | ucm/s | ||||
11. | ALA3764300 | 20 | t1/2 | = | 2.4 | hr | ALA3768363 | hr | ||||
12. | ALA3764300 | 20 | t1/2 | > | 4 | hr | ALA3768364 | hr | Rattus norvegicus | |||
13. | ALA3764300 | 20 | t1/2 | = | 1.6 | hr | ALA3768365 | hr | Homo sapiens | |||
14. | ALA3764300 | 20 | t1/2 | > | 4 | hr | ALA3768366 | hr | Canis lupus familiaris | |||
15. | ALA3764300 | 20 | CLH | = | 22.9 | ml/min.kg | ALA3768367 | mL.min-1.kg-1 | ||||
16. | ALA3764300 | 20 | CLH | < | 11.7 | ml/min.kg | ALA3768368 | mL.min-1.kg-1 | Rattus norvegicus | |||
17. | ALA3764300 | 20 | CLH | = | 12.9 | ml/min.kg | ALA3768369 | mL.min-1.kg-1 | Homo sapiens | |||
18. | ALA3764300 | 20 | CLH | < | 8.3 | ml/min.kg | ALA3768370 | mL.min-1.kg-1 | Canis lupus familiaris | |||
19. | ALA3764300 | 20 | Stability | > | 48 | hr | ALA3768371 | hr | Mus musculus | |||
20. | ALA3764300 | 20 | Stability | 0 | ALA3768372 | Not Determined | % | Rattus norvegicus |