| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3765822 | 20 | IC50 | = | 3.3 | nM | ALA3766654 | 8.48 | nM | Homo sapiens | ||
| 2. | ALA3765822 | 20 | Ratio IC50 | = | 7.6 | ALA3766655 | ||||||
| 3. | ALA3765822 | 20 | Ratio IC50 | = | 8.1 | ALA3766656 | ||||||
| 4. | ALA3765822 | 20 | Ratio IC50 | = | 1.6 | ALA3766657 | ||||||
| 5. | ALA3765822 | 20 | IC50 | = | 190 | nM | ALA3766659 | 6.72 | nM | Homo sapiens | ||
| 6. | ALA3765822 | 20 | CL | = | 1100 | ml/hr/kg | ALA3766660 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 7. | ALA3765822 | 20 | Cmax | = | 215 | ng/ml | ALA3766661 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 8. | ALA3765822 | 20 | MRT | = | 2.19 | hr | ALA3766662 | hr | Rattus norvegicus | |||
| 9. | ALA3765822 | 20 | AUC | = | 609 | ng.hr/ml | ALA3766663 | ng.hr.mL-1 | Rattus norvegicus | |||
| 10. | ALA3765822 | 20 | F | = | 67.7 | % | ALA3766664 | % | Rattus norvegicus | |||
| 11. | ALA3765822 | 20 | INH | 0 | ALA3766665 | Dose-dependent effect | % | Rattus norvegicus | ||||
| 12. | ALA3765822 | 20 | ED50 | = | 6.2 | mg kg-1 | ALA3766665 | mg.kg-1 | Rattus norvegicus | |||
| 13. | ALA3765822 | 20 | IC50 | = | 230 | nM | ALA3766658 | 6.64 | nM | Homo sapiens | ||
| 14. | ALA3765822 | 20 | IC50 | = | 65 | nM | ALA3766666 | 7.19 | nM | Homo sapiens | ||
| 15. | ALA3765822 | 20 | IC50 | = | 230 | nM | ALA3766667 | 6.64 | nM | Homo sapiens | ||
| 16. | ALA3765822 | 20 | IC50 | = | 280 | nM | ALA3766668 | 6.55 | nM | Homo sapiens | ||
| 17. | ALA3765822 | 20 | IC50 | = | 2600 | nM | ALA3766669 | 5.58 | nM | Homo sapiens | ||
| 18. | ALA3765822 | 20 | Ratio IC50 | = | 11 | ALA3766670 | ||||||
| 19. | ALA3765822 | 20 | IC50 | = | 2.1 | nM | ALA3766477 | 8.68 | nM | Homo sapiens | ||
| 20. | ALA3765822 | 20 | IC50 | = | 16 | nM | ALA3766652 | 7.80 | nM | Homo sapiens |
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