Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	PF-06761281	1a; PF-06649298	IC50	=	0.41	uM	ALA3773091	6.39	nM	Homo sapiens
2.	PF-06761281	1a; PF-06649298	pIC50	=	4.8		ALA3773092	4.80	nM	Homo sapiens
3.	PF-06761281	1a; PF-06649298	pIC50	=	6.3		ALA3773091	6.30	nM	Homo sapiens
4.	PF-06761281	1a; PF-06649298	FC	=	10		ALA3773460			Mus musculus
5.	PF-06761281	1a; PF-06649298	Fa	=	0.16		ALA3773453			Rattus norvegicus
6.	PF-06761281	1a; PF-06649298	AUCt	=	2570	ng.hr/ml	ALA3773452		ng.hr.mL-1	Rattus norvegicus
7.	PF-06761281	1a; PF-06649298	t1/2	=	1	hr	ALA3773451		hr	Rattus norvegicus
8.	PF-06761281	1a; PF-06649298	Vdss	=	0.24	L/Kg	ALA3773450		L.kg-1	Rattus norvegicus
9.	PF-06761281	1a; PF-06649298	CL	=	0.5	ml/min.kg	ALA3773449		mL.min-1.kg-1	Rattus norvegicus
10.	PF-06761281	1a; PF-06649298	CL	=	4.5	ml/min.kg	ALA3773105		mL.min-1.kg-1	Rattus norvegicus
11.	PF-06761281	1a; PF-06649298	Fu	=	0.054		ALA3773104
12.	PF-06761281	1a; PF-06649298	CLH	<	6	uL/min	ALA3773096		uL/min	Homo sapiens
13.	PF-06761281	1a; PF-06649298	Papp	=	1	ucm/s	ALA3773095		ucm/s	Canis lupus familiaris
14.	PF-06761281	1a; PF-06649298	IC50	>	100	uM	ALA3773094		nM	Homo sapiens
15.	PF-06761281	1a; PF-06649298	IC50	>	100	uM	ALA3773093		nM	Homo sapiens
16.	PF-06761281	1a; PF-06649298	IC50	=	16.2	uM	ALA3773092	4.79	nM	Homo sapiens