| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3769817 | 47 | F | = | 16 | % | ALA3772646 | % | Rattus norvegicus | |||
| 2. | ALA3769817 | 47 | AUC | = | 636 | ng.hr/ml | ALA3772645 | ng.hr.mL-1 | Rattus norvegicus | |||
| 3. | ALA3769817 | 47 | Tmax | = | 0.5 | hr | ALA3772644 | hr | Rattus norvegicus | |||
| 4. | ALA3769817 | 47 | Cmax | = | 158 | ng/ml | ALA3772643 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 5. | ALA3769817 | 47 | t1/2 | = | 1.5 | hr | ALA3772642 | hr | Rattus norvegicus | |||
| 6. | ALA3769817 | 47 | AUC | = | 420 | ng.hr/ml | ALA3772641 | ng.hr.mL-1 | Rattus norvegicus | |||
| 7. | ALA3769817 | 47 | CL | = | 40 | ml/min.kg | ALA3772640 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 8. | ALA3769817 | 47 | Vd | = | 2.48 | L/Kg | ALA3772639 | L.kg-1 | Rattus norvegicus | |||
| 9. | ALA3769817 | 47 | t1/2 | = | 0.72 | hr | ALA3772638 | hr | Rattus norvegicus | |||
| 10. | ALA3769817 | 47 | Ratio AUC | = | 0.3 | ALA3772637 | ||||||
| 11. | ALA3769817 | 47 | AUClast | = | 21 | ng.hr/ml | ALA3772636 | ng.hr.mL-1 | Mus musculus | |||
| 12. | ALA3769817 | 47 | AUClast | = | 65 | ng.hr/ml | ALA3772635 | ng.hr.mL-1 | Mus musculus | |||
| 13. | ALA3769817 | 47 | Cmax | = | 28 | ng/ml | ALA3772634 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 14. | ALA3769817 | 47 | Cmax | = | 48 | ng/ml | ALA3772633 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 15. | ALA3769817 | 47 | solubility | > | 100 | uM | ALA3772486 | nM | ||||
| 16. | ALA3769817 | 47 | logD | = | -0.58 | ALA3772485 | ||||||
| 17. | ALA3769817 | 47 | logD | = | 3.54 | ALA3772484 | ||||||
| 18. | ALA3769817 | 47 | Ki | = | 2.6 | uM | ALA3772483 | 5.58 | nM | Homo sapiens | ||
| 19. | ALA3769817 | 47 | Ki | = | 2.7 | uM | ALA3772472 | 5.57 | nM | Homo sapiens | ||
| 20. | ALA3769817 | 47 | Ki | = | 6.1 | uM | ALA3772482 | 5.21 | nM | Homo sapiens |
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