# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3774575 | 8i; IACS-9571 | IC50 | = | 8 | nM | ALA5231289 | 8.10 | nM | Homo sapiens | ||
2. | ALA3774575 | 8i; IACS-9571 | IC50 | = | 10.82 | uM | ALA5163718 | 4.97 | nM | Homo sapiens | ||
3. | ALA3774575 | 8i; IACS-9571 | IC50 | = | 12.15 | uM | ALA5163717 | 4.92 | nM | Homo sapiens | ||
4. | ALA3774575 | 8i; IACS-9571 | IC50 | = | 13.63 | uM | ALA5163716 | 4.87 | nM | Homo sapiens | ||
5. | ALA3774575 | 8i; IACS-9571 | IC50 | = | 0.15 | uM | ALA5163714 | 6.82 | nM | Homo sapiens | ||
6. | ALA3774575 | 8i; IACS-9571 | INH | = | 99.34 | % | ALA5163713 | % | Homo sapiens | |||
7. | ALA3774575 | 8i; IACS-9571 | IC50 | = | 0.011 | uM | ALA4418856 | 7.96 | nM | Homo sapiens | ||
8. | ALA3774575 | 8i; IACS-9571 | IC50 | = | 6.323 | uM | ALA4418855 | 5.20 | nM | Homo sapiens | ||
9. | ALA3774575 | 8i; IACS-9571 | inhibition | = | 1.19 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 | |||
10. | ALA3774575 | 8i; IACS-9571 | inhibition | = | 1.19 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 | |||
11. | ALA3774575 | 8i; IACS-9571 | Inhibition | = | 6.72 | % | ALA4495582 | % | Severe acute respiratory syndrome coronavirus 2 | |||
12. | ALA3774575 | 8i; IACS-9571 | IC50 | = | 0.008 | uM | ALA3779310 | 8.12 | nM | Homo sapiens | ||
13. | ALA3774575 | 8i; IACS-9571 | EC50 | = | 0.05 | uM | ALA3779314 | 7.30 | nM | Homo sapiens | ||
14. | ALA3774575 | 8i; IACS-9571 | Kinetic_solubility | = | 76 | uM | ALA3779315 | nM | ||||
15. | ALA3774575 | 8i; IACS-9571 | F | = | 29 | % | ALA3777052 | % | Mus musculus | |||
16. | ALA3774575 | 8i; IACS-9571 | beta t1/2 | = | 0.7 | hr | ALA3777051 | hr | Mus musculus | |||
17. | ALA3774575 | 8i; IACS-9571 | CL | = | 43 | ml/min.kg | ALA3777050 | mL.min-1.kg-1 | Mus musculus | |||
18. | ALA3774575 | 8i; IACS-9571 | Selectivity ratio | = | 7700 | ALA3777049 | ||||||
19. | ALA3774575 | 8i; IACS-9571 | Selectivity ratio | = | 7700 | ALA3777048 | ||||||
20. | ALA3774575 | 8i; IACS-9571 | Selectivity ratio | = | 21 | ALA3777047 |