| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  RO5256390 | 48; RO5263397 | Drug metabolism | 0 | ALA3783775 | metabolite_detected | Homo sapiens | |||||
| 2. | RO5256390 | 48; RO5263397 | Activity | 0 | ALA3783774 | Non-toxic | Salmonella enterica subsp. enterica serovar Typhimurium | |||||
| 3. | RO5256390 | 48; RO5263397 | IC50 | > | 50 | uM | ALA3783773 | nM | Homo sapiens | |||
| 4. | RO5256390 | 48; RO5263397 | IC50 | = | 32 | uM | ALA3783772 | 4.50 | nM | Homo sapiens | ||
| 5. | RO5256390 | 48; RO5263397 | IC50 | > | 50 | uM | ALA3783771 | nM | Homo sapiens | |||
| 6. | RO5256390 | 48; RO5263397 | IC20 | = | 10 | uM | ALA3783770 | uM | Homo sapiens | |||
| 7. | RO5256390 | 48; RO5263397 | Peff | = | 14.5 | 10'-6 cm/s | ALA3783769 | 10'-6 cm/s | ||||
| 8. | RO5256390 | 48; RO5263397 | logD | = | 1.12 | ALA3783768 | ||||||
| 9. | RO5256390 | 48; RO5263397 | Therm_solubility | = | 5830 | ug ml-1 | ALA3783767 | ug.mL-1 | ||||
| 10. | RO5256390 | 48; RO5263397 | pKa | = | 8.07 | ALA3783766 | ||||||
| 11. | RO5256390 | 48; RO5263397 | PB | = | 32 | pmol | ALA3783765 | pmol | Homo sapiens | |||
| 12. | RO5256390 | 48; RO5263397 | PB | = | 29 | pmol | ALA3783764 | pmol | Homo sapiens | |||
| 13. | RO5256390 | 48; RO5263397 | CLH | = | 14 | ml/min.kg | ALA3783763 | mL.min-1.kg-1 | Homo sapiens | |||
| 14. | RO5256390 | 48; RO5263397 | CLH | = | 7.7 | ml/min.kg | ALA3783762 | mL.min-1.kg-1 | Homo sapiens | |||
| 15. | RO5256390 | 48; RO5263397 | Emax | = | 69 | % | ALA3783760 | % | Rattus norvegicus | |||
| 16. | RO5256390 | 48; RO5263397 | EC50 | = | 35 | nM | ALA3783759 | 7.46 | nM | Rattus norvegicus | ||
| 17. | RO5256390 | 48; RO5263397 | Ratio EC50 | = | 1800 | ALA3783758 | ||||||
| 18. | RO5256390 | 48; RO5263397 | Emax | = | 82 | % | ALA3783757 | % | Homo sapiens | |||
| 19. | RO5256390 | 48; RO5263397 | EC50 | = | 17 | nM | ALA3783756 | 7.77 | nM | Homo sapiens |
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