| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3781349 | 6; SRI 31215 | IC50 | = | 3.2 | uM | ALA4374440 | 5.50 | nM | Homo sapiens | ||
| 2. | ALA3781349 | 6; SRI 31215 | IC50 | = | 1.9 | uM | ALA4374439 | 5.72 | nM | Homo sapiens | ||
| 3. | ALA3781349 | 6; SRI 31215 | IC50 | = | 20 | uM | ALA4374438 | 4.70 | nM | Homo sapiens | ||
| 4. | ALA3781349 | 6; SRI 31215 | IC50 | = | 0.38 | uM | ALA4374437 | 6.42 | nM | Homo sapiens | ||
| 5. | ALA3781349 | 6; SRI 31215 | IC50 | = | 11.6 | uM | ALA4374436 | 4.94 | nM | Homo sapiens | ||
| 6. | ALA3781349 | 6; SRI 31215 | F | < | 1 | % | ALA3783751 | % | Mus musculus | |||
| 7. | ALA3781349 | 6; SRI 31215 | AUC | = | 3.31 | hr.ng/ml | ALA3783750 | ng.hr.mL-1 | Mus musculus | |||
| 8. | ALA3781349 | 6; SRI 31215 | Cmax | = | 4.45 | ng/ml | ALA3783749 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 9. | ALA3781349 | 6; SRI 31215 | AUC | = | 414 | hr.ng/ml | ALA3783748 | ng.hr.mL-1 | Mus musculus | |||
| 10. | ALA3781349 | 6; SRI 31215 | Vd | = | 4489 | ml/kg | ALA3783747 | L.kg-1 | Mus musculus | |||
| 11. | ALA3781349 | 6; SRI 31215 | CL | = | 2283 | ml/hr/kg | ALA3783746 | mL.min-1.kg-1 | Mus musculus | |||
| 12. | ALA3781349 | 6; SRI 31215 | t1/2 | = | 5.8 | hr | ALA3783745 | hr | Mus musculus | |||
| 13. | ALA3781349 | 6; SRI 31215 | log Pe | = | 7.6 | ALA3783744 | ||||||
| 14. | ALA3781349 | 6; SRI 31215 | t1/2 | = | 296 | min | ALA3783743 | hr | ||||
| 15. | ALA3781349 | 6; SRI 31215 | t1/2 | = | 162 | min | ALA3783742 | hr | Homo sapiens | |||
| 16. | ALA3781349 | 6; SRI 31215 | logD | = | -0.49 | ALA3783741 | ||||||
| 17. | ALA3781349 | 6; SRI 31215 | Kinetic_solubility | = | 91.6 | uM | ALA3783740 | nM | ||||
| 18. | ALA3781349 | 6; SRI 31215 | INH | 0 | ALA3783739 | Dose-dependent effect | % | Homo sapiens | ||||
| 19. | ALA3781349 | 6; SRI 31215 | Ki | = | 0.38 | uM | ALA3782597 | 6.42 | nM | Homo sapiens | ||
| 20. | ALA3781349 | 6; SRI 31215 | Ki | = | 11.6 | uM | ALA3782596 | 4.94 | nM | Homo sapiens |
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