| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3787566 | 20 | Ratio | = | 3 | ALA3791647 | ||||||
| 2. | ALA3787566 | 20 | F | = | 52 | % | ALA3791646 | % | Rattus norvegicus | |||
| 3. | ALA3787566 | 20 | t1/2 | = | 4 | hr | ALA3791645 | hr | Rattus norvegicus | |||
| 4. | ALA3787566 | 20 | Tmax | = | 0.5 | hr | ALA3791644 | hr | Rattus norvegicus | |||
| 5. | ALA3787566 | 20 | fCmax | = | 1 | uM | ALA3789344 | uM | Rattus norvegicus | |||
| 6. | ALA3787566 | 20 | Cmax | = | 10.3 | uM | ALA3789345 | nM | Rattus norvegicus | |||
| 7. | ALA3787566 | 20 | AUC | = | 19.2 | uM.hr | ALA3791643 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
| 8. | ALA3787566 | 20 | t1/2 | = | 0.4 | hr | ALA3791642 | hr | Rattus norvegicus | |||
| 9. | ALA3787566 | 20 | Vdss | = | 1 | L/Kg | ALA3791641 | L.kg-1 | Rattus norvegicus | |||
| 10. | ALA3787566 | 20 | CL free | = | 24 | L/hr/kg | ALA3791640 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 11. | ALA3787566 | 20 | CL | = | 2.2 | L/hr/kg | ALA3791639 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 12. | ALA3787566 | 20 | Fu | = | 0.093 | ALA3789346 | Rattus norvegicus | |||||
| 13. | ALA3787566 | 20 | EC50 | > | 40 | uM | ALA3791638 | nM | Homo sapiens | |||
| 14. | ALA3787566 | 20 | EC50 | > | 40 | uM | ALA3791637 | nM | Rattus norvegicus | |||
| 15. | ALA3787566 | 20 | IC50 | = | 1.58 | uM | ALA3791636 | 5.80 | nM | Homo sapiens | ||
| 16. | ALA3787566 | 20 | IC50 | = | 0.411 | uM | ALA3791635 | 6.39 | nM | Rattus norvegicus | ||
| 17. | ALA3787566 | 20 | CLH(app) | = | 35 | microL/min/mg | ALA3789593 | mL.min-1.g-1 | Homo sapiens | |||
| 18. | ALA3787566 | 20 | CLH(app) | = | 122 | microL/min/mg | ALA3789592 | mL.min-1.g-1 | Rattus norvegicus | |||
| 19. | ALA3787566 | 20 | IC50 | = | 0.089 | uM | ALA3789591 | 7.05 | nM | Rattus norvegicus | ||
| 20. | ALA3787566 | 20 | IC50 | = | 0.156 | uM | ALA3789590 | 6.81 | nM | Homo sapiens |
The page will load shortly, Thanks for your patience!