# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3786508 | 37 | Ratio | = | 4 | ALA3789642 | ||||||
2. | ALA3786508 | 37 | Cmax | = | 6.5 | uM | ALA3789641 | nM | Rattus norvegicus | |||
3. | ALA3786508 | 37 | t1/2 | = | 10 | hr | ALA3789640 | hr | Rattus norvegicus | |||
4. | ALA3786508 | 37 | Tmax | = | 2 | hr | ALA3789639 | hr | Rattus norvegicus | |||
5. | ALA3786508 | 37 | fCmax | = | 0.2 | uM | ALA3789638 | uM | Rattus norvegicus | |||
6. | ALA3786508 | 37 | AUC | = | 117 | uM.hr | ALA3789637 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
7. | ALA3786508 | 37 | t1/2 | 0 | ALA3791642 | Not Determined | Rattus norvegicus | |||||
8. | ALA3786508 | 37 | Vdss | 0 | ALA3791641 | Not Determined | Rattus norvegicus | |||||
9. | ALA3786508 | 37 | CL | 0 | ALA3791639 | Not Determined | Rattus norvegicus | |||||
10. | ALA3786508 | 37 | Fu | = | 0.033 | ALA3789346 | Rattus norvegicus | |||||
11. | ALA3786508 | 37 | EC50 | > | 40 | uM | ALA3791638 | nM | Homo sapiens | |||
12. | ALA3786508 | 37 | EC50 | > | 40 | uM | ALA3791637 | nM | Rattus norvegicus | |||
13. | ALA3786508 | 37 | IC50 | = | 0.063 | uM | ALA3791636 | 7.20 | nM | Homo sapiens | ||
14. | ALA3786508 | 37 | IC50 | = | 0.055 | uM | ALA3791635 | 7.26 | nM | Rattus norvegicus | ||
15. | ALA3786508 | 37 | CLH(app) | < | 14 | microL/min/mg | ALA3789593 | mL.min-1.g-1 | Homo sapiens | |||
16. | ALA3786508 | 37 | CLH(app) | < | 14 | microL/min/mg | ALA3789592 | mL.min-1.g-1 | Rattus norvegicus | |||
17. | ALA3786508 | 37 | IC50 | = | 0.075 | uM | ALA3789591 | 7.12 | nM | Rattus norvegicus | ||
18. | ALA3786508 | 37 | IC50 | = | 0.071 | uM | ALA3789590 | 7.15 | nM | Homo sapiens |