# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3785583 | 121 | IC50 | = | 0.066 | uM | ALA5237436 | 7.18 | nM | Homo sapiens | ||
2. | ALA3785583 | 121 | IC50 | = | 0.005 | uM | ALA5237435 | 8.33 | nM | Homo sapiens | ||
3. | ALA3785583 | 121 | IC50 | = | 0.015 | uM | ALA5237434 | 7.82 | nM | Homo sapiens | ||
4. | ALA3785583 | 121 | Ratio | > | 15 | ALA4427174 | ||||||
5. | ALA3785583 | 121 | fCmax | = | 5.2 | uM | ALA4427173 | uM | ||||
6. | ALA3785583 | 121 | PPB | = | 97.5 | % | ALA4427172 | % | ||||
7. | ALA3785583 | 121 | Cmax | = | 206 | uM | ALA4427171 | nM | ||||
8. | ALA3785583 | 121 | Ratio IC50 | > | 100 | ALA4427170 | ||||||
9. | ALA3785583 | 121 | INH | 0 | ALA4427169 | Not Active | % | Homo sapiens | ||||
10. | ALA3785583 | 121 | INH | 0 | ALA4427168 | Not Active | % | Homo sapiens | ||||
11. | ALA3785583 | 121 | IC50 | = | 15.1 | nM | ALA4427147 | 7.82 | nM | Homo sapiens | ||
12. | ALA3785583 | 121 | EC50 | = | 340 | nM | ALA4427148 | 6.47 | nM | |||
13. | ALA3785583 | 121 | logD | = | 1.4 | ALA4427145 | ||||||
14. | ALA3785583 | 121 | PPB | = | 98.8 | % | ALA4427149 | % | ||||
15. | ALA3785583 | 121 | Papp | = | 7.5 | ALA4427150 | ||||||
16. | ALA3785583 | 121 | CLH | = | 1.5 | ml/min.kg | ALA4427152 | mL.min-1.kg-1 | ||||
17. | ALA3785583 | 121 | CLH | = | 26 | ml/min.kg | ALA4427154 | mL.min-1.kg-1 | ||||
18. | ALA3785583 | 121 | CLH | = | 13 | ml/min.kg | ALA4427153 | mL.min-1.kg-1 | ||||
19. | ALA3785583 | 121 | CLH | = | 1.9 | ml/min.kg | ALA4427155 | mL.min-1.kg-1 | ||||
20. | ALA3785583 | 121 | CLH | = | 32.6 | ml/min.kg | ALA4427156 | mL.min-1.kg-1 |