| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3785774 | 15k | CC50 | = | 14 | nM | ALA3791605 | nM | Homo sapiens | |||
| 2. | ALA3785774 | 15k | IC50 | = | 8.4 | nM | ALA3791604 | 8.08 | nM | Homo sapiens | ||
| 3. | ALA3785774 | 15k | IC50 | = | 0.5 | nM | ALA3791603 | 9.30 | nM | Homo sapiens | ||
| 4. | ALA3785774 | 15k | Activity | 0 | ALA3789303 | Non-toxic | Mus musculus | |||||
| 5. | ALA3785774 | 15k | TGI | 0 | ALA3789038 | Active | ||||||
| 6. | ALA3785774 | 15k | AUC | = | 3.76 | microg.hr/mL | ALA3789037 | ng.hr.mL-1 | Rattus norvegicus | |||
| 7. | ALA3785774 | 15k | AUCt | = | 3.75 | microg.hr/mL | ALA3789036 | ng.hr.mL-1 | Rattus norvegicus | |||
| 8. | ALA3785774 | 15k | t1/2 | = | 3.04 | hr | ALA3789035 | hr | Rattus norvegicus | |||
| 9. | ALA3785774 | 15k | Cmax | = | 1.27 | ug ml-1 | ALA3789034 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 10. | ALA3785774 | 15k | Tmax | = | 0.833 | hr | ALA3789027 | hr | Rattus norvegicus | |||
| 11. | ALA3785774 | 15k | INH | = | 43.4 | % | ALA3789033 | % | Homo sapiens | |||
| 12. | ALA3785774 | 15k | INH | = | 47.5 | % | ALA3789032 | % | Homo sapiens | |||
| 13. | ALA3785774 | 15k | INH | = | 11.4 | % | ALA3789031 | % | Homo sapiens | |||
| 14. | ALA3785774 | 15k | INH | = | 17.1 | % | ALA3789030 | % | Homo sapiens | |||
| 15. | ALA3785774 | 15k | INH | = | 7.2 | % | ALA3789029 | % | Homo sapiens | |||
| 16. | ALA3785774 | 15k | IC50 | = | 24 | uM | ALA3789028 | 4.62 | nM | Homo sapiens | ||
| 17. | ALA3785774 | 15k | Stability | = | 14 | % | ALA3791608 | % | ||||
| 18. | ALA3785774 | 15k | Stability | = | 20 | % | ALA3791607 | % | Homo sapiens | |||
| 19. | ALA3785774 | 15k | CC50 | = | 66 | nM | ALA3791606 | nM |
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