| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3785637 | 24 | Ratio | > | 1000 | ALA3791612 | ||||||
| 2. | ALA3785637 | 24 | Ratio EC50 | = | 100 | ALA3791611 | Homo sapiens | |||||
| 3. | ALA3785637 | 24 | Activity | 0 | ALA3791610 | Active | Mus musculus | |||||
| 4. | ALA3785637 | 24 | Activity | 0 | ALA3791609 | Active | Mus musculus | |||||
| 5. | ALA3785637 | 24 | CL | = | 0.49 | ml.Kg/min | ALA3791361 | ml.Kg/min | Mus musculus | |||
| 6. | ALA3785637 | 24 | AUC | = | 8295 | uM.min | ALA3791360 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
| 7. | ALA3785637 | 24 | t1/2 | = | 99 | min | ALA3791359 | hr | Mus musculus | |||
| 8. | ALA3785637 | 24 | Tmax | = | 15 | min | ALA3791358 | hr | Mus musculus | |||
| 9. | ALA3785637 | 24 | Cmax | = | 44.7 | uM | ALA3791357 | nM | Mus musculus | |||
| 10. | ALA3785637 | 24 | Drug recovery | = | 38 | % | ALA3791348 | % | ||||
| 11. | ALA3785637 | 24 | Drug recovery | = | 100 | % | ALA3791356 | % | ||||
| 12. | ALA3785637 | 24 | Drug recovery | = | 95 | % | ALA3791355 | % | ||||
| 13. | ALA3785637 | 24 | Drug recovery | = | 84 | % | ALA3791349 | % | ||||
| 14. | ALA3785637 | 24 | Drug recovery | = | 100 | % | ALA3791354 | % | ||||
| 15. | ALA3785637 | 24 | Kinetic_solubility | = | 191 | uM | ALA3791353 | nM | ||||
| 16. | ALA3785637 | 24 | logD | = | 1.79 | ALA3791352 | ||||||
| 17. | ALA3785637 | 24 | Efficacy | = | 101 | % | ALA3791351 | % | Homo sapiens | |||
| 18. | ALA3785637 | 24 | pEC50 | = | 4.7 | ALA3791350 | 4.70 | nM | Homo sapiens | |||
| 19. | ALA3785637 | 24 | Efficacy | = | 103 | % | ALA3791347 | % | Homo sapiens | |||
| 20. | ALA3785637 | 24 | EC50 | = | 20 | nM | ALA3791346 | 7.70 | nM | Homo sapiens |
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