# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3794485 | 16 | t1/2 | = | 3 | hr | ALA3796529 | hr | Mus musculus | |||
2. | ALA3794485 | 16 | Vdss | = | 10 | L/Kg | ALA3796528 | L.kg-1 | Mus musculus | |||
3. | ALA3794485 | 16 | CL | = | 4.4 | L/hr/kg | ALA3796527 | mL.min-1.kg-1 | Mus musculus | |||
4. | ALA3794485 | 16 | Tmax | = | 0.5 | hr | ALA3796526 | hr | Mus musculus | |||
5. | ALA3794485 | 16 | Tmax | = | 1 | hr | ALA3796525 | hr | Mus musculus | |||
6. | ALA3794485 | 16 | Tmax | = | 0.25 | hr | ALA3796524 | hr | Mus musculus | |||
7. | ALA3794485 | 16 | Cmax/dose | = | 56 | nM.kg/mg | ALA3796523 | nM.kg/mg | Mus musculus | |||
8. | ALA3794485 | 16 | Cmax/dose | = | 120 | nM.kg/mg | ALA3796522 | nM.kg/mg | Mus musculus | |||
9. | ALA3794485 | 16 | Cmax/dose | = | 150 | nM.kg/mg | ALA3796521 | nM.kg/mg | Mus musculus | |||
10. | ALA3794485 | 16 | AUC/dose | = | 300 | nM.hr.kg/mg | ALA3796520 | nM.hr.kg/mg | Mus musculus | |||
11. | ALA3794485 | 16 | AUC/dose | = | 580 | nM.hr.kg/mg | ALA3796519 | nM.hr.kg/mg | Mus musculus | |||
12. | ALA3794485 | 16 | AUC/dose | = | 660 | nM.hr.kg/mg | ALA3796518 | nM.hr.kg/mg | Mus musculus | |||
13. | ALA3794485 | 16 | F | = | 100 | % | ALA3796517 | % | Mus musculus | |||
14. | ALA3794485 | 16 | IC50 | = | 0.03 | uM | ALA3796508 | 7.52 | nM | Homo sapiens | ||
15. | ALA3794485 | 16 | Kd | = | 0.08 | uM | ALA3796505 | 7.10 | nM | Homo sapiens | ||
16. | ALA3794485 | 16 | Ratio | = | 1.3 | ALA3796130 | Canis lupus familiaris | |||||
17. | ALA3794485 | 16 | Papp | = | 192 | nm/s | ALA3796129 | nm/s | Canis lupus familiaris | |||
18. | ALA3794485 | 16 | CLH | < | 36 | ml/min.kg | ALA3796128 | mL.min-1.kg-1 | Homo sapiens | |||
19. | ALA3794485 | 16 | IC50 | = | 0.15 | uM | ALA3796125 | 6.82 | nM | Homo sapiens | ||
20. | ALA3794485 | 16 | Kinetic_solubility | = | 100 | uM | ALA3796126 | nM |