| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3793226 | 1; GSK945237 | Activity | 0 | ALA3795079 | Active | Streptococcus pneumoniae | |||||
| 2. | ALA3793226 | 1; GSK945237 | Activity | 0 | ALA3795017 | Active | Streptococcus pneumoniae | |||||
| 3. | ALA3793226 | 1; GSK945237 | Cmax | = | 3 | ug ml-1 | ALA3795016 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 4. | ALA3793226 | 1; GSK945237 | AUC | = | 30 | ug.hr/ml/day | ALA3795015 | ug.hr/ml/day | Rattus norvegicus | |||
| 5. | ALA3793226 | 1; GSK945237 | CL | = | 45 | % | ALA3795014 | % | Macaca fascicularis | |||
| 6. | ALA3793226 | 1; GSK945237 | CL | = | 74 | % | ALA3795013 | % | Canis lupus familiaris | |||
| 7. | ALA3793226 | 1; GSK945237 | CL | = | 40 | % | ALA3795012 | % | Macaca fascicularis | |||
| 8. | ALA3793226 | 1; GSK945237 | CL | = | 40 | % | ALA3795011 | % | Canis lupus familiaris | |||
| 9. | ALA3793226 | 1; GSK945237 | CL | = | 100 | % | ALA3795010 | % | Rattus norvegicus | |||
| 10. | ALA3793226 | 1; GSK945237 | CLH | = | 1.5 | ml/min | ALA3795009 | ml/min | ||||
| 11. | ALA3793226 | 1; GSK945237 | PPB | = | 42.45 | % | ALA3795008 | % | ||||
| 12. | ALA3793226 | 1; GSK945237 | F | = | 34 | % | ALA3795007 | % | Macaca fascicularis | |||
| 13. | ALA3793226 | 1; GSK945237 | AUC | = | 1.19 | ug.hr/L | ALA3795006 | ng.hr.mL-1 | Macaca fascicularis | |||
| 14. | ALA3793226 | 1; GSK945237 | Cmax | = | 0.21 | ug ml-1 | ALA3795005 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Macaca fascicularis | ||
| 15. | ALA3793226 | 1; GSK945237 | beta t1/2 | = | 7.6 | hr | ALA3795004 | hr | Macaca fascicularis | |||
| 16. | ALA3793226 | 1; GSK945237 | Vdss | = | 8.2 | L/Kg | ALA3795003 | L.kg-1 | Macaca fascicularis | |||
| 17. | ALA3793226 | 1; GSK945237 | CL | = | 22.6 | ml/min.kg | ALA3795002 | mL.min-1.kg-1 | Macaca fascicularis | |||
| 18. | ALA3793226 | 1; GSK945237 | CLH | < | 0.6 | ml/min | ALA3795001 | ml/min | Canis lupus familiaris | |||
| 19. | ALA3793226 | 1; GSK945237 | PPB | = | 47.03 | % | ALA3795000 | % | ||||
| 20. | ALA3793226 | 1; GSK945237 | F | = | 100 | % | ALA3794999 | % | Canis lupus familiaris |
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