| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3793506 | 14c | Activity | 0 | ALA3796439 | Non-toxic | Rattus norvegicus | |||||
| 2. | ALA3793506 | 14c | Activity | 0 | ALA3796438 | Non-toxic | Rattus norvegicus | |||||
| 3. | ALA3793506 | 14c | Activity | 0 | ALA3796437 | Non-toxic | Rattus norvegicus | |||||
| 4. | ALA3793506 | 14c | IC50 | = | 1 | nM | ALA3796436 | 9.00 | nM | |||
| 5. | ALA3793506 | 14c | INH | 0 | ALA3796435 | Active | % | Rattus norvegicus | ||||
| 6. | ALA3793506 | 14c | INH | 0 | ALA3796361 | Active | % | Rattus norvegicus | ||||
| 7. | ALA3793506 | 14c | F | = | 45 | % | ALA3796360 | % | Rattus norvegicus | |||
| 8. | ALA3793506 | 14c | Tmax | = | 4.6 | hr | ALA3796359 | hr | Rattus norvegicus | |||
| 9. | ALA3793506 | 14c | Cmax | = | 1879 | ng/ml | ALA3796358 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 10. | ALA3793506 | 14c | AUC | = | 19.9 | microg.hr/mL | ALA3796357 | ng.hr.mL-1 | Rattus norvegicus | |||
| 11. | ALA3793506 | 14c | Vdss | = | 9.1 | L/Kg | ALA3796355 | L.kg-1 | Rattus norvegicus | |||
| 12. | ALA3793506 | 14c | CL | = | 18.6 | ml/min.kg | ALA3796353 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 13. | ALA3793506 | 14c | t1/2 | = | 5.7 | hr | ALA3796351 | hr | Rattus norvegicus | |||
| 14. | ALA3793506 | 14c | AUC | = | 4.4 | microg.hr/mL | ALA3796349 | ng.hr.mL-1 | Rattus norvegicus | |||
| 15. | ALA3793506 | 14c | INH | = | 94 | % | ALA3796348 | % | ||||
| 16. | ALA3793506 | 14c | INH | = | 100 | % | ALA3796347 | % | ||||
| 17. | ALA3793506 | 14c | INH | = | 67 | % | ALA3796346 | % | Homo sapiens | |||
| 18. | ALA3793506 | 14c | INH | = | 92 | % | ALA3796345 | % | Homo sapiens | |||
| 19. | ALA3793506 | 14c | Ratio | = | 1.03 | ALA3796344 | ||||||
| 20. | ALA3793506 | 14c | Papp | = | 6.54 | ucm/s | ALA3796343 | ucm/s |
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