| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3792916 | 10a | Activity | = | 84.6 | % | ALA3796566 | % | Homo sapiens | |||
| 2. | ALA3792916 | 10a | Activity | 0 | ALA3796565 | Dose-dependent effect | Homo sapiens | |||||
| 3. | ALA3792916 | 10a | logP | = | 1.91 | ALA3796568 | ||||||
| 4. | ALA3792916 | 10a | F | = | 4 | % | ALA3796567 | % | Rattus norvegicus | |||
| 5. | ALA3792916 | 10a | Activity | 0 | ALA3796564 | Non-toxic | Homo sapiens | |||||
| 6. | ALA3792916 | 10a | Activity | = | 84.6 | % | ALA3796563 | % | Homo sapiens | |||
| 7. | ALA3792916 | 10a | Activity | 0 | ALA3796562 | Dose-dependent effect | Homo sapiens | |||||
| 8. | ALA3792916 | 10a | CL(app) | = | 71.2 | L/hr/kg | ALA3796561 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 9. | ALA3792916 | 10a | beta t1/2 | = | 5.64 | hr | ALA3796560 | hr | Rattus norvegicus | |||
| 10. | ALA3792916 | 10a | IC50 | = | 0.19 | nM | ALA3796469 | 9.72 | nM | Homo sapiens | ||
| 11. | ALA3792916 | 10a | IC50 | = | 1579.01 | nM | ALA3796470 | 5.80 | nM | Homo sapiens | ||
| 12. | ALA3792916 | 10a | Ratio IC50 | = | 8310 | ALA3796552 | Homo sapiens | |||||
| 13. | ALA3792916 | 10a | AUC | = | 3068.05 | ug.hr/L | ALA3796468 | ng.hr.mL-1 | Rattus norvegicus | |||
| 14. | ALA3792916 | 10a | AUC | = | 3209.16 | ug.hr/L | ALA3796553 | ng.hr.mL-1 | Rattus norvegicus | |||
| 15. | ALA3792916 | 10a | Vz | = | 1.43 | L/Kg | ALA3796554 | L.kg-1 | Rattus norvegicus | |||
| 16. | ALA3792916 | 10a | beta t1/2 | = | 7.88 | hr | ALA3796555 | hr | Rattus norvegicus | |||
| 17. | ALA3792916 | 10a | CL(app) | = | 3.13 | L/hr/kg | ALA3796556 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 18. | ALA3792916 | 10a | AUC | = | 36.18 | ug.hr/L | ALA3796557 | ng.hr.mL-1 | Rattus norvegicus | |||
| 19. | ALA3792916 | 10a | AUC | = | 140.44 | ug.hr/L | ALA3796558 | ng.hr.mL-1 | Rattus norvegicus | |||
| 20. | ALA3792916 | 10a | Vz | = | 579.41 | L/Kg | ALA3796559 | L.kg-1 | Rattus norvegicus |
The page will load shortly, Thanks for your patience!