| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3798741 | EPZ031686 | Drugexcretion | = | 20 | %ID | ALA3803414 | %ID | ||||
| 2. | ALA3798741 | EPZ031686 | F | = | 69 | % | ALA3803413 | % | Mus musculus | |||
| 3. | ALA3798741 | EPZ031686 | AUC | = | 21170 | hr.ng/ml | ALA3803412 | ng.hr.mL-1 | Mus musculus | |||
| 4. | ALA3798741 | EPZ031686 | AUClast | = | 21158 | hr.ng/ml | ALA3803411 | ng.hr.mL-1 | Mus musculus | |||
| 5. | ALA3798741 | EPZ031686 | Cmax | = | 4693 | ng/ml | ALA3803410 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 6. | ALA3798741 | EPZ031686 | Tmax | = | 1.3 | hr | ALA3803409 | hr | Mus musculus | |||
| 7. | ALA3798741 | EPZ031686 | beta t1/2 | = | 2.2 | hr | ALA3803408 | hr | Mus musculus | |||
| 8. | ALA3798741 | EPZ031686 | F | = | 48 | % | ALA3803407 | % | Mus musculus | |||
| 9. | ALA3798741 | EPZ031686 | AUC | = | 1479 | hr.ng/ml | ALA3803406 | ng.hr.mL-1 | Mus musculus | |||
| 10. | ALA3798741 | EPZ031686 | AUClast | = | 1281 | hr.ng/ml | ALA3803405 | ng.hr.mL-1 | Mus musculus | |||
| 11. | ALA3798741 | EPZ031686 | Ki | = | 1.1 | nM | ALA3803390 | 8.96 | nM | Homo sapiens | ||
| 12. | ALA3798741 | EPZ031686 | Ki | = | 1.2 | nM | ALA3803391 | 8.92 | nM | Homo sapiens | ||
| 13. | ALA3798741 | EPZ031686 | CLH | = | 24 | ml/min.kg | ALA3803392 | mL.min-1.kg-1 | ||||
| 14. | ALA3798741 | EPZ031686 | Papp | = | 0.64 | ucm/s | ALA3803393 | ucm/s | ||||
| 15. | ALA3798741 | EPZ031686 | Ratio | = | 41 | ALA3803394 | ||||||
| 16. | ALA3798741 | EPZ031686 | Fu | = | 0.53 | ALA3803395 | ||||||
| 17. | ALA3798741 | EPZ031686 | CL | = | 27 | ml/min.kg | ALA3803396 | mL.min-1.kg-1 | Mus musculus | |||
| 18. | ALA3798741 | EPZ031686 | CL | = | 5.3 | ml/min.kg | ALA3803397 | mL.min-1.kg-1 | Mus musculus | |||
| 19. | ALA3798741 | EPZ031686 | Vdss | = | 2.3 | L/Kg | ALA3803398 | L.kg-1 | Mus musculus | |||
| 20. | ALA3798741 | EPZ031686 | beta t1/2 | = | 1.7 | hr | ALA3803399 | hr | Mus musculus |
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