# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3799913 | 11 | t1/2 | = | 0.4 | hr | ALA3801505 | hr | Rattus norvegicus | |||
2. | ALA3799913 | 11 | Vd | = | 1.9 | L/Kg | ALA3801504 | L.kg-1 | Rattus norvegicus | |||
3. | ALA3799913 | 11 | Drug uptake | = | 410 | nM | ALA3801503 | nM | Rattus norvegicus | |||
4. | ALA3799913 | 11 | Drug uptake | 0 | ALA3801502 | BLD | Rattus norvegicus | |||||
5. | ALA3799913 | 11 | Cp | = | 3600 | nM | ALA3801501 | nM | Rattus norvegicus | |||
6. | ALA3799913 | 11 | Cp | = | 70 | nM | ALA3801500 | nM | Rattus norvegicus | |||
7. | ALA3799913 | 11 | INH | 0 | ALA3801499 | Dose-dependent effect | % | Rattus norvegicus | ||||
8. | ALA3799913 | 11 | INH | 0 | ALA3801498 | Dose-dependent effect | % | Rattus norvegicus | ||||
9. | ALA3799913 | 11 | CL | = | 94 | ml/min.kg | ALA3801497 | mL.min-1.kg-1 | Rattus norvegicus | |||
10. | ALA3799913 | 11 | CLH | = | 448 | ml/min.kg | ALA3801496 | mL.min-1.kg-1 | ||||
11. | ALA3799913 | 11 | CLH | = | 74 | ml/min.kg | ALA3801495 | mL.min-1.kg-1 | Homo sapiens | |||
12. | ALA3799913 | 11 | IC50 | = | 40 | nM | ALA3801492 | 7.40 | nM | Homo sapiens | ||
13. | ALA3799913 | 11 | IC50 | = | 3020 | nM | ALA3801493 | 5.52 | nM | Homo sapiens | ||
14. | ALA3799913 | 11 | IC50 | = | 15 | nM | ALA3801494 | 7.82 | nM | Rattus norvegicus |