# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | LY3130481 | (-)-25; LY3130481 | INH | 0 | ALA3825278 | Dose-dependent effect | % | Rattus norvegicus | ||||
2. | LY3130481 | (-)-25; LY3130481 | TD50 | = | 3.8 | mg kg-1 | ALA3824694 | mg kg-1 | Rattus norvegicus | |||
3. | LY3130481 | (-)-25; LY3130481 | Ratio TD50/ED50 | > | 58 | ALA3825308 | Rattus norvegicus | |||||
4. | LY3130481 | (-)-25; LY3130481 | Activity | 0 | ALA3825306 | Non-toxic | Rattus norvegicus | |||||
5. | LY3130481 | (-)-25; LY3130481 | Cp | = | 1780 | ng/ml | ALA3825293 | ng/ml | Rattus norvegicus | |||
6. | LY3130481 | (-)-25; LY3130481 | Cp | = | 8342 | ng/ml | ALA3825305 | ng/ml | Rattus norvegicus | |||
7. | LY3130481 | (-)-25; LY3130481 | Drug uptake | = | 2400 | ng/g | ALA3825304 | ng/g | Rattus norvegicus | |||
8. | LY3130481 | (-)-25; LY3130481 | Drug uptake | = | 1526 | ng/g | ALA3825303 | ng/g | Rattus norvegicus | |||
9. | LY3130481 | (-)-25; LY3130481 | Drug uptake | = | 477 | ng/g | ALA3825302 | ng/g | Rattus norvegicus | |||
10. | LY3130481 | (-)-25; LY3130481 | Drug uptake | = | 133 | ng/g | ALA3825301 | ng/g | Rattus norvegicus | |||
11. | LY3130481 | (-)-25; LY3130481 | Occ | = | 96 | % | ALA3825300 | % | Rattus norvegicus | |||
12. | LY3130481 | (-)-25; LY3130481 | Occ | = | 68 | % | ALA3825299 | % | Rattus norvegicus | |||
13. | LY3130481 | (-)-25; LY3130481 | Occ | = | 69 | % | ALA3825298 | % | Rattus norvegicus | |||
14. | LY3130481 | (-)-25; LY3130481 | Occ | = | 45 | % | ALA3825297 | % | Rattus norvegicus | |||
15. | LY3130481 | (-)-25; LY3130481 | Cp | = | 3360 | ng/ml | ALA3825296 | ng/ml | Rattus norvegicus | |||
16. | LY3130481 | (-)-25; LY3130481 | Cp | = | 1269 | ng/ml | ALA3825295 | ng/ml | Rattus norvegicus | |||
17. | LY3130481 | (-)-25; LY3130481 | Cp | = | 377 | ng/ml | ALA3825294 | ng/ml | Rattus norvegicus | |||
18. | LY3130481 | (-)-25; LY3130481 | INH | = | 100 | % | ALA3825292 | % | Rattus norvegicus | |||
19. | LY3130481 | (-)-25; LY3130481 | INH | = | 80 | % | ALA3825291 | % | Rattus norvegicus | |||
20. | LY3130481 | (-)-25; LY3130481 | INH | = | 40 | % | ALA3825290 | % | Rattus norvegicus |