Activities

#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid	5c; Table 2, 9.12	EC50	=	154	nM	ALA3876466	6.81		nM	Homo sapiens
2.	4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid	5c; Table 2, 9.12	Activity		0		ALA3876465				Cricetulus griseus
3.	4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid	5c; Table 2, 9.12	Activity		0		ALA3876464				Homo sapiens
4.	4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid	5c; Table 2, 9.12	Activity		0		ALA3876463				Homo sapiens
5.	4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid	5c; Table 2, 9.12	Activity		0		ALA3876462		Active		Homo sapiens
6.	4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid	5c; Table 2, 9.12	Activity		0		ALA3876461				Homo sapiens
7.	4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid	5c; Table 2, 9.12	Activity		0		ALA3876458		Active		Homo sapiens
8.	4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid	5c; Table 2, 9.12	Activity		0		ALA3876457		Active		Homo sapiens
9.	4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid	5c; Table 2, 9.12	Activity		0		ALA3876455				Homo sapiens
10.	4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid	5c; Table 2, 9.12	EC50	>	100	uM	ALA3876453			nM	Homo sapiens
11.	4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid	5c; Table 2, 9.12	EC50	>	100	uM	ALA3876452			nM	Homo sapiens
12.	4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid	5c; Table 2, 9.12	EC50	>	100	uM	ALA3876451			nM	Homo sapiens
13.	4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid	5c; Table 2, 9.12	Efficacy	=	24	%	ALA3876450			%	Homo sapiens
14.	4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid	5c; Table 2, 9.12	EC50	=	0.2	uM	ALA3876449	6.70		nM	Homo sapiens
15.	4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid	5c; Table 2, 9.12	EC50	=	0.37	uM	ALA3876448	6.43		nM	Homo sapiens

1.

4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid

5c; Table 2, 9.12

EC50

=

154

nM

ALA3876466

6.81

nM

Homo sapiens

2.

4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid

5c; Table 2, 9.12

Activity

0

ALA3876465

Cricetulus griseus

3.

4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid

5c; Table 2, 9.12

Activity

0

ALA3876464

Homo sapiens

4.

4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid

5c; Table 2, 9.12

Activity

0

ALA3876463

Homo sapiens

5.

4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid

5c; Table 2, 9.12

Activity

0

ALA3876462

Active

Homo sapiens

6.

4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid

5c; Table 2, 9.12

Activity

0

ALA3876461

Homo sapiens

7.

4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid

5c; Table 2, 9.12

Activity

0

ALA3876458

Active

Homo sapiens

8.

4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid

5c; Table 2, 9.12

Activity

0

ALA3876457

Active

Homo sapiens

9.

4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid

5c; Table 2, 9.12

Activity

0

ALA3876455

Homo sapiens

10.

4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid

5c; Table 2, 9.12

EC50

>

100

uM

ALA3876453

nM

Homo sapiens

11.

4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid

5c; Table 2, 9.12

EC50

>

100

uM

ALA3876452

nM

Homo sapiens

12.

4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid

5c; Table 2, 9.12

EC50

>

100

uM

ALA3876451

nM

Homo sapiens

13.

4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid

5c; Table 2, 9.12

Efficacy

=

24

%

ALA3876450

%

Homo sapiens

14.

4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid

5c; Table 2, 9.12

EC50

=

0.2

uM

ALA3876449

6.70

nM

Homo sapiens

15.

4-({[7-(naphthalen-2-yl)-1-benzothiophen-2-yl]methyl}amino)butanoic acid

5c; Table 2, 9.12

EC50

=

0.37

uM

ALA3876448

6.43

nM

Homo sapiens