# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3891994 | BDBM226354 | IC50 | = | 12.36 | nM | ALA3888383 | 7.91 | 396135 | nM | Homo sapiens | |
2. | ALA3891994 | BDBM226354 | Activity | 0 | ALA4309243 | Non-Toxic | ||||||
3. | ALA3891994 | BDBM226354 | Drug uptake | < | 5 | % | ALA4309242 | % | ||||
4. | ALA3891994 | BDBM226354 | Ratio | = | 90 | ALA4309241 | ||||||
5. | ALA3891994 | BDBM226354 | Ratio | = | 230 | ALA4309240 | ||||||
6. | ALA3891994 | BDBM226354 | Ratio | = | 2.7 | ALA4309239 | ||||||
7. | ALA3891994 | BDBM226354 | Ratio | = | 0.4 | ALA4309238 | ||||||
8. | ALA3891994 | BDBM226354 | Activity | 0 | ALA4309237 | Non-Toxic | Rattus norvegicus | |||||
9. | ALA3891994 | BDBM226354 | Activity | 0 | ALA4309235 | Active | Rattus norvegicus | |||||
10. | ALA3891994 | BDBM226354 | IC50 | = | 6 | nM | ALA4309234 | 8.22 | nM | Rattus norvegicus | ||
11. | ALA3891994 | BDBM226354 | IC50 | = | 57 | nM | ALA4309233 | 7.24 | nM | Rattus norvegicus | ||
12. | ALA3891994 | BDBM226354 | Activity | 0 | ALA4309232 | Not Active | Homo sapiens | |||||
13. | ALA3891994 | BDBM226354 | Activity | 0 | ALA4309228 | Non-Toxic | Cricetulus griseus | |||||
14. | ALA3891994 | BDBM226354 | Activity | 0 | ALA4309227 | Non-Toxic | Cricetulus griseus | |||||
15. | ALA3891994 | BDBM226354 | Activity | 0 | ALA4309226 | Non-Toxic | ||||||
16. | ALA3891994 | BDBM226354 | Activity | 0 | ALA4309224 | Non-Toxic | ||||||
17. | ALA3891994 | BDBM226354 | F | = | 72 | % | ALA4309222 | % | ||||
18. | ALA3891994 | BDBM226354 | Tmax | = | 4 | hr | ALA4309220 | hr | ||||
19. | ALA3891994 | BDBM226354 | Vd | = | 2.8 | L/Kg | ALA4309218 | L.kg-1 | ||||
20. | ALA3891994 | BDBM226354 | CL | = | 11.9 | ml/min.kg | ALA4309216 | mL.min-1.kg-1 |