# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3897809 | BDBM205428 | Ki | = | 13 | nM | ALA3887929 | 7.89 | 363871 | nM | Homo sapiens | |
2. | ALA3897809 | BDBM205428 | FC | = | 11.69 | ALA4355744 | Rattus norvegicus | |||||
3. | ALA3897809 | BDBM205428 | AUC | = | 35.91 | nM.hr/g | ALA4355743 | nM.hr/g | ||||
4. | ALA3897809 | BDBM205428 | Tmax | = | 8 | hr | ALA4355746 | hr | ||||
5. | ALA3897809 | BDBM205428 | FC | = | 2.04 | ALA4355745 | Rattus norvegicus | |||||
6. | ALA3897809 | BDBM205428 | BPR | = | 0.189 | ALA4355773 | ||||||
7. | ALA3897809 | BDBM205428 | Drug uptake | = | 0.142 | nmol/g | ALA4355771 | nmol/g | ||||
8. | ALA3897809 | BDBM205428 | FC | = | 2.51 | ALA4355769 | Rattus norvegicus | |||||
9. | ALA3897809 | BDBM205428 | F | = | 90.4 | % | ALA4355768 | % | ||||
10. | ALA3897809 | BDBM205428 | Vdss | = | 2.96 | L/Kg | ALA4355765 | L.kg-1 | ||||
11. | ALA3897809 | BDBM205428 | t1/2 | = | 4.29 | hr | ALA4355762 | hr | ||||
12. | ALA3897809 | BDBM205428 | CL | = | 11.4 | ml/min.kg | ALA4355760 | mL.min-1.kg-1 | ||||
13. | ALA3897809 | BDBM205428 | AUC/dose | = | 4.27 | uM.hr.kg/mg | ALA4355759 | uM.hr.kg/mg | ||||
14. | ALA3897809 | BDBM205428 | Fu | = | 93 | % | ALA4355757 | |||||
15. | ALA3897809 | BDBM205428 | EC50 | = | 58.2 | nM | ALA4355755 | 7.24 | nM | Rattus norvegicus | ||
16. | ALA3897809 | BDBM205428 | Ki | = | 23 | nM | ALA4355754 | 7.64 | nM | Homo sapiens | ||
17. | ALA3897809 | BDBM205428 | Fu | = | 97 | % | ALA4355753 | |||||
18. | ALA3897809 | BDBM205428 | Papp | = | 20 | 10'-6 cm/s | ALA4355751 | 10'-6 cm/s | ||||
19. | ALA3897809 | BDBM205428 | Ki | > | 10000 | nM | ALA4355756 | nM | Homo sapiens |