# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3902148 | BDBM238724 | Fu | 0 | ALA4478486 | Not Determined | ||||||
2. | ALA3902148 | BDBM238724 | Fu | = | 6.2 | % | ALA4478485 | |||||
3. | ALA3902148 | BDBM238724 | Ratio | = | 23.3 | ALA4478484 | ||||||
4. | ALA3902148 | BDBM238724 | Ratio | = | 20.3 | ALA4478483 | ||||||
5. | ALA3902148 | BDBM238724 | Ratio | = | 2.4 | ALA4478482 | ||||||
6. | ALA3902148 | BDBM238724 | Papp | = | 16 | 10'-6 cm/s | ALA4478481 | 10'-6 cm/s | ||||
7. | ALA3902148 | BDBM238724 | solubility | = | 23 | uM | ALA4478474 | nM | ||||
8. | ALA3902148 | BDBM238724 | solubility | = | 14 | uM | ALA4478473 | nM | ||||
9. | ALA3902148 | BDBM238724 | F | = | 10 | % | ALA4478472 | % | ||||
10. | ALA3902148 | BDBM238724 | t1/2 | = | 4.3 | hr | ALA4478471 | hr | ||||
11. | ALA3902148 | BDBM238724 | Vdss | = | 1.4 | L/Kg | ALA4478470 | L.kg-1 | ||||
12. | ALA3902148 | BDBM238724 | CL | = | 0.4 | L/hr/kg | ALA4478469 | mL.min-1.kg-1 | ||||
13. | ALA3902148 | BDBM238724 | CLH | < | 14 | microL/min/mg | ALA4478468 | mL.min-1.g-1 | ||||
14. | ALA3902148 | BDBM238724 | CLH | = | 16 | microL/min/mg | ALA4478467 | mL.min-1.g-1 | ||||
15. | ALA3902148 | BDBM238724 | IC50 | = | 26 | nM | ALA4478466 | 7.58 | nM | Homo sapiens | ||
16. | ALA3902148 | BDBM238724 | IC50 | = | 0.1 | nM | ALA4478465 | 10.00 | nM | Homo sapiens | ||
17. | ALA3902148 | BDBM238724 | IC50 | = | 0.1 | nM | ALA4478464 | 10.00 | nM | Homo sapiens | ||
18. | ALA3902148 | BDBM238724 | IC50 | = | 0.012 | nM | ALA3888800 | 10.92 | 416833 | nM | Homo sapiens | |
19. | ALA3902148 | BDBM238724 | IC50 | = | 0.012 | nM | ALA3888799 | 10.92 | 416513 | nM | Homo sapiens |