# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3915941 | 25 | IC50 | = | 0.2 | nM | ALA3855037 | 9.70 | nM | Homo sapiens | ||
2. | ALA3915941 | 25 | IC50 | = | 12.8 | nM | ALA3855038 | 7.89 | nM | Rattus norvegicus | ||
3. | ALA3915941 | 25 | Drug uptake | = | 680 | nM | ALA3855052 | nM | ||||
4. | ALA3915941 | 25 | Drug uptake | = | 0.21 | uM | ALA3855053 | uM | ||||
5. | ALA3915941 | 25 | Drug uptake | = | 0.75 | uM | ALA3855054 | uM | ||||
6. | ALA3915941 | 25 | Drug uptake | = | 1.9 | uM | ALA3855055 | uM | ||||
7. | ALA3915941 | 25 | F | = | 90 | % | ALA3855058 | % | ||||
8. | ALA3915941 | 25 | Activity | = | 14.3 | % | ALA3855059 | % | ||||
9. | ALA3915941 | 25 | MED | = | 0.03 | mg kg-1 | ALA3855060 | mg kg-1 | ||||
10. | ALA3915941 | 25 | Occ | = | 81 | % | ALA3855050 | % | Rattus norvegicus | |||
11. | ALA3915941 | 25 | Drug uptake | = | 1304 | nM | ALA3855047 | nM | ||||
12. | ALA3915941 | 25 | Occ | = | 88 | % | ALA3855044 | % | Rattus norvegicus | |||
13. | ALA3915941 | 25 | t1/2 | = | 14 | hr | ALA3855057 | hr | ||||
14. | ALA3915941 | 25 | solubility | > | 1 | mg/ml | ALA3855042 | ug.mL-1 | ||||
15. | ALA3915941 | 25 | IC50 | = | 5 | uM | ALA3855041 | 5.30 | nM | Homo sapiens | ||
16. | ALA3915941 | 25 | IC50 | = | 5 | uM | ALA3855040 | 5.30 | nM | Homo sapiens | ||
17. | ALA3915941 | 25 | IC50 | > | 30 | uM | ALA3855039 | nM | Homo sapiens | |||
18. | ALA3915941 | 25 | permeability | = | 4.7 | % | ALA3855036 | % |