# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3917415 | BDBM210853 | Ratio | = | 53 | ALA4049122 | ||||||
2. | ALA3917415 | BDBM210853 | Ratio | = | 26 | ALA4049121 | ||||||
3. | ALA3917415 | BDBM210853 | IC50 | = | 1043 | nM | ALA4049090 | 5.98 | nM | Homo sapiens | ||
4. | ALA3917415 | BDBM210853 | IC50 | = | 2700 | nM | ALA4049089 | 5.57 | nM | Homo sapiens | ||
5. | ALA3917415 | BDBM210853 | IC50 | >= | 25000 | nM | ALA4049088 | nM | Homo sapiens | |||
6. | ALA3917415 | BDBM210853 | IC50 | = | 9000 | nM | ALA4049087 | 5.05 | nM | Homo sapiens | ||
7. | ALA3917415 | BDBM210853 | IC50 | = | 4 | nM | ALA4049086 | 8.40 | nM | Trypanosoma brucei brucei | ||
8. | ALA3917415 | BDBM210853 | Drug uptake | = | 4.8 | ng/ml | ALA4049085 | ng/ml | Mus musculus | |||
9. | ALA3917415 | BDBM210853 | Drug uptake | = | 15.1 | ng/ml | ALA4049084 | ng/ml | Mus musculus | |||
10. | ALA3917415 | BDBM210853 | Drug uptake | = | 237 | ng/ml | ALA4049083 | ng/ml | Mus musculus | |||
11. | ALA3917415 | BDBM210853 | Survival | = | 16.3 | day | ALA4049082 | day | Trypanosoma brucei rhodesiense | |||
12. | ALA3917415 | BDBM210853 | Time | <= | 10.25 | day | ALA4049081 | hr | Trypanosoma brucei rhodesiense | |||
13. | ALA3917415 | BDBM210853 | Drug metabolism | > | 98 | % | ALA4049080 | % | Rattus norvegicus | |||
14. | ALA3917415 | BDBM210853 | Drug metabolism | > | 98 | % | ALA4049079 | % | Rattus norvegicus | |||
15. | ALA3917415 | BDBM210853 | Drug metabolism | > | 98 | % | ALA4049078 | % | Homo sapiens | |||
16. | ALA3917415 | BDBM210853 | IC50 | = | 0.01 | uM | ALA4049077 | 8.00 | nM | Trypanosoma brucei rhodesiense | ||
17. | ALA3917415 | BDBM210853 | Ratio | = | 0.006 | ALA4049076 | ||||||
18. | ALA3917415 | BDBM210853 | BPR | = | 0.7 | ALA4049075 | ||||||
19. | ALA3917415 | BDBM210853 | Drug uptake | = | 2.3 | ng/ml | ALA4049074 | ng/ml | Rattus norvegicus | |||
20. | ALA3917415 | BDBM210853 | Drug uptake | = | 256 | ng/g | ALA4049073 | ng/g | Rattus norvegicus |