| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3931344 | 12 | IC50 | = | 3.9 | nM | ALA3873577 | 8.41 | nM | Homo sapiens | ||
| 2. | ALA3931344 | 12 | Activity | = | 76 | % | ALA4181384 | % | Homo sapiens | |||
| 3. | ALA3931344 | 12 | Ratio | = | 2 | ALA4181382 | ||||||
| 4. | ALA3931344 | 12 | Activity | 0 | ALA4181381 | Dose-dependent effect | Cavia porcellus | |||||
| 5. | ALA3931344 | 12 | ED50 | = | 14.3 | mg kg-1 | ALA4181381 | mg.kg-1 | Cavia porcellus | |||
| 6. | ALA3931344 | 12 | Cp | = | 371 | nM | ALA4181380 | nM | ||||
| 7. | ALA3931344 | 12 | Cp | = | 116 | ng/ml | ALA4181379 | ng/ml | ||||
| 8. | ALA3931344 | 12 | Cp | = | 43 | ng/ml | ALA4181378 | ng/ml | ||||
| 9. | ALA3931344 | 12 | Activity | = | 61 | % | ALA4181377 | % | Cavia porcellus | |||
| 10. | ALA3931344 | 12 | Activity | = | 42 | % | ALA4181376 | % | Cavia porcellus | |||
| 11. | ALA3931344 | 12 | Activity | = | 0 | % | ALA4181375 | % | Cavia porcellus | |||
| 12. | ALA3931344 | 12 | t1/2 | = | 1.1 | hr | ALA4181373 | hr | Rattus norvegicus | |||
| 13. | ALA3931344 | 12 | Ratio IC50 | = | 30 | ALA4181372 | ||||||
| 14. | ALA3931344 | 12 | Selectivity ratio | > | 1000 | ALA4181371 | ||||||
| 15. | ALA3931344 | 12 | Selectivity ratio | > | 1000 | ALA4181370 | ||||||
| 16. | ALA3931344 | 12 | Selectivity ratio | > | 1000 | ALA4181369 | ||||||
| 17. | ALA3931344 | 12 | Selectivity ratio | > | 1000 | ALA4181368 | ||||||
| 18. | ALA3931344 | 12 | Cp | = | 268.9 | ng/ml | ALA4181367 | ng/ml | ||||
| 19. | ALA3931344 | 12 | Drug uptake | = | 58.9 | ng/ml | ALA4181366 | ng/ml | ||||
| 20. | ALA3931344 | 12 | Vz | = | 1.67 | L/Kg | ALA4181365 | L.kg-1 | Macaca fascicularis |
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