| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3933749 | 25 | IC50 | = | 20.3 | uM | ALA4322077 | 4.69 | nM | Homo sapiens | ||
| 2. | ALA3933749 | 25 | IC50 | = | 0.073 | uM | ALA4322076 | 7.14 | nM | Homo sapiens | ||
| 3. | ALA3933749 | 25 | Papp | 0 | ALA3869688 | Permeable | ||||||
| 4. | ALA3933749 | 25 | Cp(f)max | = | 83 | uM | ALA3869687 | uM | ||||
| 5. | ALA3933749 | 25 | Activity | 0 | ALA3869686 | Non-Toxic | ||||||
| 6. | ALA3933749 | 25 | Activity | = | -12 | mmHg | ALA3869685 | mmHg | ||||
| 7. | ALA3933749 | 25 | FC | = | 1.05 | ALA3869684 | ||||||
| 8. | ALA3933749 | 25 | Activity | = | -16 | mmHg | ALA3869683 | mmHg | ||||
| 9. | ALA3933749 | 25 | FC | = | 1.8 | ALA3869682 | ||||||
| 10. | ALA3933749 | 25 | Activity | = | -16 | mmHg | ALA3869681 | mmHg | ||||
| 11. | ALA3933749 | 25 | FC | = | 1.6 | ALA3869680 | ||||||
| 12. | ALA3933749 | 25 | Activity | = | -9 | mmHg | ALA3869679 | mmHg | ||||
| 13. | ALA3933749 | 25 | FC | = | 1.4 | ALA3869678 | ||||||
| 14. | ALA3933749 | 25 | F | = | 67 | % | ALA3869676 | % | ||||
| 15. | ALA3933749 | 25 | t1/2 | = | 5 | hr | ALA3869675 | hr | ||||
| 16. | ALA3933749 | 25 | AUC/dose | = | 6 | uM.hr.kg/mg | ALA3869674 | uM.hr.kg/mg | ||||
| 17. | ALA3933749 | 25 | CL | = | 4 | L/Kg | ALA3869635 | L/Kg | ||||
| 18. | ALA3933749 | 25 | F | = | 100 | % | ALA3869673 | % | ||||
| 19. | ALA3933749 | 25 | t1/2 | = | 17.3 | hr | ALA3869672 | hr | ||||
| 20. | ALA3933749 | 25 | AUC/dose | = | 16.7 | uM.hr.kg/mg | ALA3869671 | uM.hr.kg/mg |
The page will load shortly, Thanks for your patience!