| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3948914 | 25 | INH | 0 | ALA3878790 | Dose-dependent effect | % | Mus musculus | ||||
| 2. | ALA3948914 | 25 | Kd | = | 108 | nM | ALA3878789 | 6.97 | nM | Homo sapiens | ||
| 3. | ALA3948914 | 25 | Ki | = | 22.8 | nM | ALA3878788 | 7.64 | nM | Rattus norvegicus | ||
| 4. | ALA3948914 | 25 | IC50 | = | 74.3 | nM | ALA3878788 | 7.13 | nM | Rattus norvegicus | ||
| 5. | ALA3948914 | 25 | F | = | 3.7 | % | ALA3878787 | % | ||||
| 6. | ALA3948914 | 25 | BPR | = | 1.02 | ALA3878786 | ||||||
| 7. | ALA3948914 | 25 | BPR | = | 2.88 | ALA3878785 | ||||||
| 8. | ALA3948914 | 25 | Drugexcretion | = | 0.01 | % | ALA3878784 | % | ||||
| 9. | ALA3948914 | 25 | Drugexcretion | = | 0.03 | % | ALA3878783 | % | ||||
| 10. | ALA3948914 | 25 | Vdss | = | 6205.39 | ml/kg | ALA3878782 | L.kg-1 | ||||
| 11. | ALA3948914 | 25 | MRT | = | 67.14 | min | ALA3878781 | hr | ||||
| 12. | ALA3948914 | 25 | CL | = | 54.55 | ml/min.kg | ALA3878780 | mL.min-1.kg-1 | ||||
| 13. | ALA3948914 | 25 | Tmax | = | 33 | min | ALA3878779 | hr | ||||
| 14. | ALA3948914 | 25 | Cmax | = | 0.07 | ug ml-1 | ALA3878778 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 15. | ALA3948914 | 25 | beta t1/2 | = | 89.25 | min | ALA3878777 | hr | ||||
| 16. | ALA3948914 | 25 | beta t1/2 | = | 157.48 | min | ALA3878776 | hr | ||||
| 17. | ALA3948914 | 25 | AUClast | = | 7.68 | microg.min/mL | ALA3878775 | ng.hr.mL-1 | ||||
| 18. | ALA3948914 | 25 | AUClast | = | 104.75 | microg.min/mL | ALA3878774 | ng.hr.mL-1 | ||||
| 19. | ALA3948914 | 25 | AUC | = | 8.17 | microg.min/mL | ALA3878773 | ng.hr.mL-1 | ||||
| 20. | ALA3948914 | 25 | AUC | = | 111.02 | microg.min/mL | ALA3878772 | ng.hr.mL-1 |
The page will load shortly, Thanks for your patience!