# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3950704 | BDBM238767 | IC50 | = | 0.364 | nM | ALA3888800 | 9.44 | 416876 | nM | Homo sapiens | |
2. | ALA3950704 | BDBM238767 | IC50 | = | 0.238 | nM | ALA3888799 | 9.62 | 416556 | nM | Homo sapiens | |
3. | ALA3950704 | BDBM238767 | Fu | 0 | ALA4478486 | Not Determined | ||||||
4. | ALA3950704 | BDBM238767 | Fu | = | 6.1 | % | ALA4478485 | |||||
5. | ALA3950704 | BDBM238767 | Ratio | = | 11.8 | ALA4478484 | ||||||
6. | ALA3950704 | BDBM238767 | Ratio | = | 5.9 | ALA4478483 | ||||||
7. | ALA3950704 | BDBM238767 | Ratio | = | 1.2 | ALA4478482 | ||||||
8. | ALA3950704 | BDBM238767 | Papp | = | 29 | 10'-6 cm/s | ALA4478481 | 10'-6 cm/s | ||||
9. | ALA3950704 | BDBM238767 | Ratio IC50 | = | 30 | ALA4478480 | ||||||
10. | ALA3950704 | BDBM238767 | solubility | = | 344 | uM | ALA4478474 | nM | ||||
11. | ALA3950704 | BDBM238767 | solubility | = | 56 | uM | ALA4478473 | nM | ||||
12. | ALA3950704 | BDBM238767 | F | = | 5 | % | ALA4478472 | % | ||||
13. | ALA3950704 | BDBM238767 | t1/2 | = | 0.6 | hr | ALA4478471 | hr | ||||
14. | ALA3950704 | BDBM238767 | Vdss | = | 1.9 | L/Kg | ALA4478470 | L.kg-1 | ||||
15. | ALA3950704 | BDBM238767 | CL | = | 2.7 | L/hr/kg | ALA4478469 | mL.min-1.kg-1 | ||||
16. | ALA3950704 | BDBM238767 | CLH | = | 20 | microL/min/mg | ALA4478468 | mL.min-1.g-1 | ||||
17. | ALA3950704 | BDBM238767 | CLH | = | 49 | microL/min/mg | ALA4478467 | mL.min-1.g-1 | ||||
18. | ALA3950704 | BDBM238767 | IC50 | = | 11 | nM | ALA4478466 | 7.96 | nM | Homo sapiens | ||
19. | ALA3950704 | BDBM238767 | IC50 | = | 0.4 | nM | ALA4478465 | 9.40 | nM | Homo sapiens | ||
20. | ALA3950704 | BDBM238767 | IC50 | = | 0.2 | nM | ALA4478464 | 9.70 | nM | Homo sapiens |