# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA18264 | MF-tricyclic | ED50 | = | 0.5 | mg kg-1 | ALA4394093 | mg.kg-1 | Mus musculus | |||
2. | ALA18264 | MF-tricyclic | IC50 | = | 2.8 | uM | ALA4394092 | 5.55 | nM | Oryctolagus cuniculus | ||
3. | ALA18264 | MF-tricyclic | IC50 | = | 0.6 | uM | ALA4394091 | 6.22 | nM | Cavia porcellus | ||
4. | ALA18264 | MF-tricyclic | ED50 | = | 0.5 | mg kg-1 | ALA1074447 | mg.kg-1 | Rattus norvegicus | |||
5. | ALA18264 | MF-tricyclic | INH | = | 70 | % | ALA1074446 | % | Rattus norvegicus | |||
6. | ALA18264 | MF-tricyclic | Selectivity | = | 15 | ALA829659 | Homo sapiens | |||||
7. | ALA18264 | MF-tricyclic | IC50 | = | 0.9 | uM | ALA876993 | 6.05 | nM | Homo sapiens | ||
8. | ALA18264 | MF-tricyclic | IC50 | = | 13 | uM | ALA832839 | 4.89 | nM | Homo sapiens | ||
9. | ALA18264 | MF-tricyclic | IC50 | > | 50 | uM | ALA768751 | nM | Homo sapiens | |||
10. | ALA18264 | MF-tricyclic | IC50 | = | 0.03 | uM | ALA763082 | 7.52 | nM | Homo sapiens | ||
11. | ALA18264 | MF-tricyclic | IC50 | = | 13 | uM | ALA768750 | 4.89 | nM | Homo sapiens | ||
12. | ALA18264 | MF-tricyclic | IC50 | = | 0.9 | uM | ALA763081 | 6.05 | nM | Homo sapiens | ||
13. | ALA18264 | MF-tricyclic | IC50 | = | 15.3 | uM | ALA768837 | 4.82 | nM | Homo sapiens | ||
14. | ALA18264 | MF-tricyclic | IC50 | = | 0.48 | uM | ALA769652 | 6.32 | nM | Homo sapiens | ||
15. | ALA18264 | MF-tricyclic | IC50 | > | 100 | uM | ALA763483 | nM | Homo sapiens | |||
16. | ALA18264 | MF-tricyclic | IC50 | = | 0.23 | uM | ALA768962 | 6.64 | nM | Homo sapiens |