# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3965757 | 22p | IC50 | = | 0.3 | nM | ALA3887609 | 9.52 | 344683 | nM | Homo sapiens | |
2. | ALA3965757 | 22p | IC50 | < | 0.1 | nM | ALA3887608 | 344617 | nM | Homo sapiens | ||
3. | ALA3965757 | 22p | IC50 | = | 19.7 | uM | ALA3864816 | 4.71 | nM | Homo sapiens | ||
4. | ALA3965757 | 22p | F | = | 141 | % | ALA3864815 | % | ||||
5. | ALA3965757 | 22p | AUC | = | 3.3 | uM.hr | ALA3864814 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
6. | ALA3965757 | 22p | MRT | = | 4 | hr | ALA3864813 | hr | ||||
7. | ALA3965757 | 22p | Vdss | = | 21.7 | L/Kg | ALA3864812 | L.kg-1 | ||||
8. | ALA3965757 | 22p | CL | = | 5.5 | L/hr/kg | ALA3864811 | mL.min-1.kg-1 | ||||
9. | ALA3965757 | 22p | CLH | = | 203 | uL/min.mg | ALA3864810 | mL.min-1.g-1 | ||||
10. | ALA3965757 | 22p | CLH | > | 399 | uL/min.mg | ALA3864809 | mL.min-1.g-1 | ||||
11. | ALA3965757 | 22p | IC50 | = | 49 | nM | ALA3864807 | 7.31 | nM | Homo sapiens | ||
12. | ALA3965757 | 22p | IC50 | = | 0.31 | nM | ALA3864806 | 9.51 | nM | Homo sapiens | ||
13. | ALA3965757 | 22p | IC50 | = | 0.021 | nM | ALA3864805 | 10.68 | nM | Homo sapiens |