# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3973097 | 47 | K | = | 0.21 | /s | ALA3868363 | /s | Homo sapiens | |||
2. | ALA3973097 | 47 | K | = | 4.43 | 10'7/M/s | ALA3868362 | 10'7/M/s | Homo sapiens | |||
3. | ALA3973097 | 47 | Kd | = | 4.74 | nM | ALA3868361 | 8.32 | nM | Homo sapiens | ||
4. | ALA3973097 | 47 | PPB | = | 84 | % | ALA3868360 | % | ||||
5. | ALA3973097 | 47 | PPB | = | 83 | % | ALA3868359 | % | ||||
6. | ALA3973097 | 47 | Papp | = | 33 | 10'-6 cm/s | ALA3868358 | 10'-6 cm/s | ||||
7. | ALA3973097 | 47 | Ratio | = | 1.1 | ALA3868357 | ||||||
8. | ALA3973097 | 47 | F | = | 16 | % | ALA3868355 | % | ||||
9. | ALA3973097 | 47 | t1/2 | = | 2 | hr | ALA3868354 | hr | ||||
10. | ALA3973097 | 47 | CL | = | 25 | ml/min.kg | ALA3868353 | mL.min-1.kg-1 | ||||
11. | ALA3973097 | 47 | F | = | 63 | % | ALA3868352 | % | ||||
12. | ALA3973097 | 47 | t1/2 | = | 1 | hr | ALA3868351 | hr | ||||
13. | ALA3973097 | 47 | CL | = | 12 | ml/min.kg | ALA3868350 | mL.min-1.kg-1 | ||||
14. | ALA3973097 | 47 | t1/2 | = | 3.2 | hr | ALA3868349 | hr | ||||
15. | ALA3973097 | 47 | CLH | = | 189 | ml/min.kg | ALA3868348 | mL.min-1.kg-1 | ||||
16. | ALA3973097 | 47 | CLH | < | 75 | ml/min.kg | ALA3868323 | mL.min-1.kg-1 | ||||
17. | ALA3973097 | 47 | CLH | = | 55 | ml/min.kg | ALA3868330 | mL.min-1.kg-1 | ||||
18. | ALA3973097 | 47 | IC50 | > | 10000 | nM | ALA3868324 | nM | Rattus norvegicus | |||
19. | ALA3973097 | 47 | CLH | = | 267 | ml/min.kg | ALA3868325 | mL.min-1.kg-1 | ||||
20. | ALA3973097 | 47 | F | = | 22 | % | ALA3868332 | % |