# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3981509 | 40 | Ratio EC50 | = | 10 | ALA4005346 | ||||||
2. | ALA3981509 | 40 | Ratio IC50/EC50 | = | 2 | ALA4005345 | Homo sapiens | |||||
3. | ALA3981509 | 40 | AUC | = | 4.5 | ug.hr/kg | ALA4005276 | ug.hr/kg | Rattus norvegicus | |||
4. | ALA3981509 | 40 | Vdss | = | 1.1 | l | ALA4005275 | l | Rattus norvegicus | |||
5. | ALA3981509 | 40 | CL | = | 0.6 | L/hr/kg | ALA4005274 | mL.min-1.kg-1 | Rattus norvegicus | |||
6. | ALA3981509 | 40 | F | = | 24 | % | ALA4005273 | % | Rattus norvegicus | |||
7. | ALA3981509 | 40 | beta t1/2 | = | 3.2 | hr | ALA4005272 | hr | Rattus norvegicus | |||
8. | ALA3981509 | 40 | Tmax | = | 0.833 | hr | ALA4005271 | hr | Rattus norvegicus | |||
9. | ALA3981509 | 40 | Cmax | = | 1.43 | ug ml-1 | ALA4005270 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
10. | ALA3981509 | 40 | t1/2 | > | 60 | min | ALA4005269 | hr | ||||
11. | ALA3981509 | 40 | t1/2 | > | 60 | min | ALA4005268 | hr | ||||
12. | ALA3981509 | 40 | IC50 | = | 19 | nM | ALA4005267 | 7.72 | nM | Homo sapiens | ||
13. | ALA3981509 | 40 | EC50 | = | 640 | nM | ALA4005262 | 6.19 | nM | Rattus norvegicus | ||
14. | ALA3981509 | 40 | Intrinsic activity | = | 88 | % | ALA4005263 | % | Homo sapiens | |||
15. | ALA3981509 | 40 | EC50 | = | 10 | nM | ALA4005264 | 8.00 | nM | Homo sapiens | ||
16. | ALA3981509 | 40 | EC50 | = | 5000 | nM | ALA4005265 | 5.30 | nM | Homo sapiens | ||
17. | ALA3981509 | 40 | Intrinsic activity | = | 95 | % | ALA4005261 | % | Rattus norvegicus | |||
18. | ALA3981509 | 40 | Intrinsic activity | = | 45 | % | ALA4005266 | % | Homo sapiens | |||
19. | ALA3981509 | 40 | IC50 | = | 0.011 | uM | ALA3881324 | 7.98 | nM | |||
20. | ALA3981509 | 40 | EC50 | = | 0.003 | uM | ALA3881323 | 8.57 | nM | Homo sapiens |