# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3989951 | NAVOXIMOD | Ki | = | 28 | nM | ALA5216253 | 7.55 | nM | Homo sapiens | ||
2. | ALA3989951 | NAVOXIMOD | EC50 | = | 3 | uM | ALA5215725 | 5.52 | nM | Homo sapiens | ||
3. | ALA3989951 | NAVOXIMOD | EC50 | = | 1.51 | uM | ALA5215724 | 5.82 | nM | Homo sapiens | ||
4. | ALA3989951 | NAVOXIMOD | EC50 | = | 0.1 | uM | ALA5215723 | 7.00 | nM | Homo sapiens | ||
5. | ALA3989951 | NAVOXIMOD | IC50 | = | 0.15 | uM | ALA5215722 | 6.82 | nM | Homo sapiens | ||
6. | ALA3989951 | NAVOXIMOD | IC50 | = | 0.081 | uM | ALA5215721 | 7.09 | nM | Homo sapiens | ||
7. | ALA3989951 | NAVOXIMOD | Ki | = | 19 | nM | ALA5215716 | 7.72 | nM | Homo sapiens | ||
8. | ALA3989951 | NAVOXIMOD | IC50 | = | 28 | nM | ALA5137950 | 7.55 | nM | Homo sapiens | ||
9. | ALA3989951 | NAVOXIMOD | IC50 | = | 13 | nM | ALA4143450 | 7.89 | nM | Homo sapiens | ||
10. | ALA3989951 | NAVOXIMOD | IC50 | = | 75 | nM | ALA4143452 | 7.12 | nM | Homo sapiens | ||
11. | ALA3989951 | NAVOXIMOD | IC50 | = | 140 | nM | ALA4143459 | 6.85 | nM | Homo sapiens | ||
12. | ALA3989951 | NAVOXIMOD | IC50 | = | 1.5 | uM | ALA4143460 | 5.82 | nM | Homo sapiens | ||
13. | ALA3989951 | NAVOXIMOD | Fu | = | 52 | % | ALA4367358 | |||||
14. | ALA3989951 | NAVOXIMOD | AUC | = | 22550 | hr.ng/ml | ALA4367357 | ng.hr.mL-1 | ||||
15. | ALA3989951 | NAVOXIMOD | AUC | = | 22500 | hr.ng/ml | ALA4367356 | ng.hr.mL-1 | ||||
16. | ALA3989951 | NAVOXIMOD | NOAEL | = | 200 | mg kg-1 | ALA4367355 | mg kg-1 | ||||
17. | ALA3989951 | NAVOXIMOD | NOAEL | = | 250 | mg kg-1 | ALA4367354 | mg kg-1 | ||||
18. | ALA3989951 | NAVOXIMOD | Activity | 0 | ALA4367353 | Active | Mus musculus | |||||
19. | ALA3989951 | NAVOXIMOD | Activity | 0 | ALA4367352 | Active | Mus musculus | |||||
20. | ALA3989951 | NAVOXIMOD | Activity | 0 | ALA4367351 | Active | Mus musculus |