| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3990145 | 13 | Ratio | > | 5 | ALA4122898 | Macaca fascicularis | |||||
| 2. | ALA3990145 | 13 | INH | 0 | ALA4122897 | Dose-dependent effect | % | Macaca fascicularis | ||||
| 3. | ALA3990145 | 13 | F | = | 25 | % | ALA4122896 | % | Macaca fascicularis | |||
| 4. | ALA3990145 | 13 | Tmax | = | 1.67 | hr | ALA4122895 | hr | Macaca fascicularis | |||
| 5. | ALA3990145 | 13 | Cmax | = | 29.1 | ng/ml | ALA4122894 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Macaca fascicularis | ||
| 6. | ALA3990145 | 13 | AUC | = | 323 | ng.hr/ml | ALA4122893 | ng.hr.mL-1 | Macaca fascicularis | |||
| 7. | ALA3990145 | 13 | CL | = | 855 | ml/hr/kg | ALA4122892 | mL.min-1.kg-1 | Macaca fascicularis | |||
| 8. | ALA3990145 | 13 | AUC | = | 128 | ng.hr/ml | ALA4122891 | ng.hr.mL-1 | Macaca fascicularis | |||
| 9. | ALA3990145 | 13 | Ratio IC50 | = | 200 | ALA4122890 | ||||||
| 10. | ALA3990145 | 13 | IC50 | = | 1.5 | nM | ALA4122889 | 8.82 | nM | Macaca mulatta | ||
| 11. | ALA3990145 | 13 | IC50 | = | 310 | nM | ALA4122888 | 6.51 | nM | Rattus norvegicus | ||
| 12. | ALA3990145 | 13 | permeability | = | 345 | nm/s | ALA4122886 | nm/s | ||||
| 13. | ALA3990145 | 13 | F | = | 14 | % | ALA4122885 | % | Rattus norvegicus | |||
| 14. | ALA3990145 | 13 | IC50 | = | 0.84 | nM | ALA4122879 | 9.08 | nM | Homo sapiens | ||
| 15. | ALA3990145 | 13 | IC50 | = | 1.4 | nM | ALA4122880 | 8.85 | nM | Homo sapiens | ||
| 16. | ALA3990145 | 13 | logD | = | 2.11 | ALA4122881 | ||||||
| 17. | ALA3990145 | 13 | AUC | = | 68 | ng.hr/ml | ALA4122882 | ng.hr.mL-1 | Rattus norvegicus | |||
| 18. | ALA3990145 | 13 | AUC | = | 92.2 | ng.hr/ml | ALA4122883 | ng.hr.mL-1 | Rattus norvegicus | |||
| 19. | ALA3990145 | 13 | CL | = | 1554 | ml/hr/kg | ALA4122884 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 20. | ALA3990145 | 13 | IC50 | = | 0.43 | nM | ALA4122878 | 9.37 | nM | Homo sapiens |
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