# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3991199 | fostriecin | MIC | = | 50 | uM | ALA3225343 | nM | ||||
2. | ALA3991199 | fostriecin | IC50 | = | 5.1 | uM | ALA3225342 | 5.29 | nM | |||
3. | ALA3991199 | fostriecin | IC50 | = | 0.46 | uM | ALA3225341 | 6.34 | nM | Mus musculus | ||
4. | ALA3991199 | fostriecin | IC50 | = | 1.5 | nM | ALA3225344 | 8.82 | nM | |||
5. | ALA3991199 | fostriecin | Hepatotoxicity (mechanism) | 0 | ALA3137740 | Dose-dependant | ||||||
6. | ALA3991199 | fostriecin | Hepatotoxicity (time to onset) | 0 | ALA3137739 | |||||||
7. | ALA3991199 | fostriecin | Hepatotoxicity (comment) | 0 | ALA3137738 | |||||||
8. | ALA3991199 | fostriecin | Hepatotoxicity (successful reintroduction) | 0 | ALA3137737 | |||||||
9. | ALA3991199 | fostriecin | Hepatotoxicity (animal toxicity known) | 0 | ALA3137736 | |||||||
10. | ALA3991199 | fostriecin | Hepatotoxicity (benign tumour) | = | 0 | ALA3137735 | references out of a total of 1 | |||||
11. | ALA3991199 | fostriecin | Hepatotoxicity (malignant tumour) | = | 0 | ALA3137734 | references out of a total of 1 | |||||
12. | ALA3991199 | fostriecin | Hepatotoxicity (steatosis) | = | 0 | ALA3137733 | references out of a total of 1 | |||||
13. | ALA3991199 | fostriecin | Hepatotoxicity (association with vascular disease) | = | 0 | ALA3137732 | references out of a total of 1 | |||||
14. | ALA3991199 | fostriecin | Hepatotoxicity (granulomatous hepatitis) | = | 0 | ALA3137731 | references out of a total of 1 | |||||
15. | ALA3991199 | fostriecin | Hepatotoxicity (cirrhosis) | = | 0 | ALA3137730 | references out of a total of 1 | |||||
16. | ALA3991199 | fostriecin | Hepatotoxicity (chronic liver disease) | = | 0 | ALA3137729 | references out of a total of 1 | |||||
17. | ALA3991199 | fostriecin | Hepatotoxicity (severe hepatitis) | = | 0 | ALA3137728 | references out of a total of 1 | |||||
18. | ALA3991199 | fostriecin | Hepatotoxicity (choleostasis) | = | 0 | ALA3137727 | references out of a total of 1 | |||||
19. | ALA3991199 | fostriecin | Hepatotoxicity (cytolytic) | = | 0 | ALA3137726 | references out of a total of 1 | |||||
20. | ALA3991199 | fostriecin | Hepatotoxicity (acute) | = | 0 | % | ALA3137725 | % |