# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4060201 | 24 | F | = | 1.4 | % | ALA4031357 | % | Rattus norvegicus | |||
2. | ALA4060201 | 24 | AUC | = | 12.3 | hr.ng/ml | ALA4031356 | ng.hr.mL-1 | Rattus norvegicus | |||
3. | ALA4060201 | 24 | Cmax | = | 15.9 | ng/ml | ALA4031355 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
4. | ALA4060201 | 24 | Tmax | = | 0.083 | hr | ALA4031354 | hr | Rattus norvegicus | |||
5. | ALA4060201 | 24 | beta t1/2 | = | 0.58 | hr | ALA4031353 | hr | Rattus norvegicus | |||
6. | ALA4060201 | 24 | Vdss | = | 1.49 | L/Kg | ALA4031352 | L.kg-1 | Rattus norvegicus | |||
7. | ALA4060201 | 24 | CL | = | 95.1 | ml/min.kg | ALA4031293 | mL.min-1.kg-1 | Rattus norvegicus | |||
8. | ALA4060201 | 24 | AUC | = | 175.2 | hr.ng/ml | ALA4031351 | ng.hr.mL-1 | Rattus norvegicus | |||
9. | ALA4060201 | 24 | beta t1/2 | = | 0.35 | hr | ALA4031350 | hr | Rattus norvegicus | |||
10. | ALA4060201 | 24 | Drug uptake | 0 | ALA4031370 | Not Active | Rattus norvegicus | |||||
11. | ALA4060201 | 24 | Drug uptake | 0 | ALA4031369 | Active | Rattus norvegicus | |||||
12. | ALA4060201 | 24 | INH | 0 | ALA4031367 | Active | % | Homo sapiens | ||||
13. | ALA4060201 | 24 | INH | 0 | ALA4031366 | Active | % | Homo sapiens | ||||
14. | ALA4060201 | 24 | Ratio IC50 | = | 335 | ALA4031294 | ||||||
15. | ALA4060201 | 24 | Activity | 0 | ALA4031365 | Dose-dependent effect | Homo sapiens | |||||
16. | ALA4060201 | 24 | Activity | 0 | ALA4031364 | Dose-dependent effect | Homo sapiens | |||||
17. | ALA4060201 | 24 | INH | 0 | ALA4031363 | Active | % | Homo sapiens | ||||
18. | ALA4060201 | 24 | INH | 0 | ALA4031362 | Active | % | Homo sapiens | ||||
19. | ALA4060201 | 24 | INH | 0 | ALA4031361 | Active | % | Homo sapiens | ||||
20. | ALA4060201 | 24 | INH | 0 | ALA4031360 | Active | % | Homo sapiens |