# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4060775 | 5h | IC50 | = | 8.5 | nM | ALA4026559 | 8.07 | nM | Rattus norvegicus | ||
2. | ALA4060775 | 5h | IC50 | = | 4.1 | nM | ALA4026560 | 8.39 | nM | Homo sapiens | ||
3. | ALA4060775 | 5h | Stability | = | 201 | ml/min/mg | ALA4026561 | ml/min/mg | Homo sapiens | |||
4. | ALA4060775 | 5h | Stability | = | 234 | ml/min/mg | ALA4026562 | ml/min/mg | Mus musculus | |||
5. | ALA4060775 | 5h | Drug metabolism | = | 17.2 | % | ALA4026563 | % | ||||
6. | ALA4060775 | 5h | Drug metabolism | = | 46.5 | % | ALA4026564 | % | ||||
7. | ALA4060775 | 5h | Drug metabolism | = | 12.9 | % | ALA4026565 | % | ||||
8. | ALA4060775 | 5h | Drug metabolism | = | 31.5 | % | ALA4026566 | % | ||||
9. | ALA4060775 | 5h | Drug metabolism | 0 | ALA4026567 | Metabolite_Notdetected | ||||||
10. | ALA4060775 | 5h | Drug metabolism | 0 | ALA4026568 | Metabolite_Notdetected | ||||||
11. | ALA4060775 | 5h | Drug metabolism | 0 | ALA4026569 | Metabolite_Notdetected | ||||||
12. | ALA4060775 | 5h | Drug metabolism | = | 110.7 | % | ALA4026570 | % | ||||
13. | ALA4060775 | 5h | Drug metabolism | = | 29.8 | % | ALA4026571 | % | ||||
14. | ALA4060775 | 5h | Drug metabolism | = | 23.1 | % | ALA4026572 | % | ||||
15. | ALA4060775 | 5h | Drug metabolism | 0 | ALA4026573 | Metabolite_Notdetected | ||||||
16. | ALA4060775 | 5h | Drug metabolism | 0 | ALA4026574 | Metabolite_Notdetected | ||||||
17. | ALA4060775 | 5h | Drug metabolism | = | 0.51 | ug/g | ALA4026575 | ug/g | Mus musculus | |||
18. | ALA4060775 | 5h | Drug metabolism | = | 4.41 | ug/g | ALA4026576 | ug/g | Mus musculus | |||
19. | ALA4060775 | 5h | Drug metabolism | 0 | ALA4026577 | Metabolite_Notdetected | Mus musculus | |||||
20. | ALA4060775 | 5h | Drug metabolism | = | 0.83 | ug/g | ALA4026578 | ug/g | Mus musculus |