# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4062193 | 22 | Drug uptake(free) | = | 7 | nM | ALA4036843 | nM | ||||
2. | ALA4062193 | 22 | Drug uptake | = | 20 | ug/g | ALA4036842 | ug/g | ||||
3. | ALA4062193 | 22 | Drug uptake | = | 304 | ug/g | ALA4036841 | ug/g | ||||
4. | ALA4062193 | 22 | permeability | = | 1.2 | 10'-5cm/hr | ALA4036840 | 10'-5cm/hr | ||||
5. | ALA4062193 | 22 | Activity | 0 | ALA4036838 | Active | Rattus norvegicus | |||||
6. | ALA4062193 | 22 | IC50 | = | 11 | nM | ALA4036831 | 7.96 | nM | Rattus norvegicus | ||
7. | ALA4062193 | 22 | Ratio IC50 | > | 1000 | ALA4036830 | ||||||
8. | ALA4062193 | 22 | EC50 | > | 10 | uM | ALA4036829 | nM | Homo sapiens | |||
9. | ALA4062193 | 22 | IC50 | > | 30 | uM | ALA4036828 | nM | Homo sapiens | |||
10. | ALA4062193 | 22 | IC50 | = | 8700 | nM | ALA4036827 | 5.06 | nM | Homo sapiens | ||
11. | ALA4062193 | 22 | IC50 | = | 18200 | nM | ALA4036826 | 4.74 | nM | Homo sapiens | ||
12. | ALA4062193 | 22 | IC50 | > | 100 | uM | ALA4036825 | nM | Homo sapiens | |||
13. | ALA4062193 | 22 | IC50 | = | 0.33 | uM | ALA4036824 | 6.48 | nM | Homo sapiens | ||
14. | ALA4062193 | 22 | solubility | = | 1.6 | ug ml-1 | ALA4036823 | ug.mL-1 | ||||
15. | ALA4062193 | 22 | Ratio | = | 4 | ALA4036822 | Canis lupus familiaris | |||||
16. | ALA4062193 | 22 | permeability | = | 7 | 10'-6 cm/s | ALA4036820 | 10'-6 cm/s | Canis lupus familiaris | |||
17. | ALA4062193 | 22 | permeability | = | 2 | 10'-6 cm/s | ALA4036821 | 10'-6 cm/s | Canis lupus familiaris | |||
18. | ALA4062193 | 22 | CLH | = | 99 | microL/min/mg | ALA4036819 | mL.min-1.g-1 | Rattus norvegicus | |||
19. | ALA4062193 | 22 | CLH | = | 73 | microL/min/mg | ALA4036818 | mL.min-1.g-1 | Homo sapiens | |||
20. | ALA4062193 | 22 | IC50 | = | 16 | uM | ALA4036817 | 4.80 | nM | Homo sapiens |