| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4063342 | 17h.Dihydrochloride salt | Cp | = | 7.1 | ng/ml | ALA4055657 | ng/ml | Rattus norvegicus | |||
| 2. | ALA4063342 | 17h.Dihydrochloride salt | Cp | = | 111 | ng/ml | ALA4055656 | ng/ml | Rattus norvegicus | |||
| 3. | ALA4063342 | 17h.Dihydrochloride salt | INH | 0 | ALA4055655 | Active | % | Rattus norvegicus | ||||
| 4. | ALA4063342 | 17h.Dihydrochloride salt | INH | 0 | ALA4055654 | Active | % | Rattus norvegicus | ||||
| 5. | ALA4063342 | 17h.Dihydrochloride salt | F | = | 17.4 | % | ALA4055653 | % | Rattus norvegicus | |||
| 6. | ALA4063342 | 17h.Dihydrochloride salt | Vdss | = | 0.386 | L/Kg | ALA4055652 | L.kg-1 | Rattus norvegicus | |||
| 7. | ALA4063342 | 17h.Dihydrochloride salt | t1/2 | = | 1.29 | hr | ALA4055651 | hr | Rattus norvegicus | |||
| 8. | ALA4063342 | 17h.Dihydrochloride salt | t1/2 | = | 1.39 | hr | ALA4055650 | hr | Rattus norvegicus | |||
| 9. | ALA4063342 | 17h.Dihydrochloride salt | CL | = | 8.69 | ml/min.kg | ALA4055649 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 10. | ALA4063342 | 17h.Dihydrochloride salt | Cmax | = | 113 | ng/ml | ALA4055648 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 11. | ALA4063342 | 17h.Dihydrochloride salt | AUC | = | 334 | ng.hr/ml | ALA4055647 | ng.hr.mL-1 | Rattus norvegicus | |||
| 12. | ALA4063342 | 17h.Dihydrochloride salt | AUC | = | 1920 | ng.hr/ml | ALA4055646 | ng.hr.mL-1 | Rattus norvegicus | |||
| 13. | ALA4063342 | 17h.Dihydrochloride salt | solubility | = | 89.6 | uM | ALA4055645 | nM | ||||
| 14. | ALA4063342 | 17h.Dihydrochloride salt | solubility | = | 2.3 | uM | ALA4055644 | nM | ||||
| 15. | ALA4063342 | 17h.Dihydrochloride salt | INH | = | 62 | % | ALA4055643 | % | Rattus norvegicus | |||
| 16. | ALA4063342 | 17h.Dihydrochloride salt | INH | = | 64 | % | ALA4055642 | % | Rattus norvegicus | |||
| 17. | ALA4063342 | 17h.Dihydrochloride salt | INH | = | 93 | % | ALA4055641 | % | Rattus norvegicus | |||
| 18. | ALA4063342 | 17h.Dihydrochloride salt | INH | = | 96 | % | ALA4055640 | % | Rattus norvegicus | |||
| 19. | ALA4063342 | 17h.Dihydrochloride salt | Activity | = | 109 | % | ALA4055639 | % | Homo sapiens | |||
| 20. | ALA4063342 | 17h.Dihydrochloride salt | Activity | = | 98 | % | ALA4055638 | % | Homo sapiens |
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