| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4064760 | 17 | Vdss | = | 7 | L/Kg | ALA4004337 | L.kg-1 | Macaca mulatta | |||
| 2. | ALA4064760 | 17 | CL | = | 57 | ml/min.Kg | ALA4004336 | mL.min-1.kg-1 | Macaca mulatta | |||
| 3. | ALA4064760 | 17 | t1/2 | = | 1.8 | hr | ALA4004335 | hr | Macaca mulatta | |||
| 4. | ALA4064760 | 17 | AUCt | = | 0.61 | uM.hr | ALA4004334 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Macaca mulatta | ||
| 5. | ALA4064760 | 17 | F | = | 67 | % | ALA4004333 | % | Canis lupus familiaris | |||
| 6. | ALA4064760 | 17 | Vdss | = | 17.8 | L/Kg | ALA4004332 | L.kg-1 | Canis lupus familiaris | |||
| 7. | ALA4064760 | 17 | CL | = | 42 | ml/min.Kg | ALA4004331 | mL.min-1.kg-1 | Canis lupus familiaris | |||
| 8. | ALA4064760 | 17 | t1/2 | = | 8.6 | hr | ALA4004330 | hr | Canis lupus familiaris | |||
| 9. | ALA4064760 | 17 | AUCt | = | 0.75 | uM.hr | ALA4004329 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Canis lupus familiaris | ||
| 10. | ALA4064760 | 17 | IC50 | = | 0.04 | uM | ALA4004328 | 7.40 | nM | Rattus norvegicus | ||
| 11. | ALA4064760 | 17 | Cp | = | 0.078 | uM | ALA4004325 | uM | Rattus norvegicus | |||
| 12. | ALA4064760 | 17 | Activity | = | -19.9 | mmHg | ALA4004323 | mmHg | Rattus norvegicus | |||
| 13. | ALA4064760 | 17 | Ratio IC50 | = | 614 | ALA4004322 | ||||||
| 14. | ALA4064760 | 17 | IC50 | = | 22.7 | uM | ALA4004321 | 4.64 | nM | Homo sapiens | ||
| 15. | ALA4064760 | 17 | IC50 | = | 37 | nM | ALA4004320 | 7.43 | nM | Homo sapiens | ||
| 16. | ALA4064760 | 17 | F | = | 37 | % | ALA4004318 | % | Rattus norvegicus | |||
| 17. | ALA4064760 | 17 | t1/2 | = | 2.1 | hr | ALA4004317 | hr | Rattus norvegicus | |||
| 18. | ALA4064760 | 17 | Vd | = | 5.6 | L/Kg | ALA4004316 | L.kg-1 | Rattus norvegicus | |||
| 19. | ALA4064760 | 17 | AUC/dose | = | 0.4 | uM.hr.kg/mg | ALA4004315 | uM.hr.kg/mg | Rattus norvegicus | |||
| 20. | ALA4064760 | 17 | CL | = | 37 | L/Kg | ALA4004314 | L/Kg | Rattus norvegicus |
The page will load shortly, Thanks for your patience!