# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4064834 | 30; GSK428 | solubility | > | 25 | mg/ml | ALA4012398 | ug.mL-1 | ||||
2. | ALA4064834 | 30; GSK428 | Vd | = | 0.52 | L/Kg | ALA4012390 | L.kg-1 | Rattus norvegicus | |||
3. | ALA4064834 | 30; GSK428 | CL | = | 4.7 | ml/min.kg | ALA4012391 | mL.min-1.kg-1 | Rattus norvegicus | |||
4. | ALA4064834 | 30; GSK428 | t1/2 | = | 3.7 | hr | ALA4012409 | hr | Rattus norvegicus | |||
5. | ALA4064834 | 30; GSK428 | pIC50 | = | 5.9 | ALA4012417 | 5.90 | nM | Rattus norvegicus | |||
6. | ALA4064834 | 30; GSK428 | INH | 0 | ALA4012413 | Active | % | Rattus norvegicus | ||||
7. | ALA4064834 | 30; GSK428 | Activity | 0 | ALA4012412 | Non-Toxic | Mus musculus | |||||
8. | ALA4064834 | 30; GSK428 | Fu | = | 9.5 | % | ALA4012411 | Rattus norvegicus | ||||
9. | ALA4064834 | 30; GSK428 | Ratio | = | 0.56 | ALA4012410 | ||||||
10. | ALA4064834 | 30; GSK428 | Stability | < | 0.01 | ml/min | ALA4012408 | ml/min | ||||
11. | ALA4064834 | 30; GSK428 | Stability | < | 0.01 | ml/min/mg | ALA4012407 | ml/min/mg | ||||
12. | ALA4064834 | 30; GSK428 | Activity | 0 | ALA4012406 | Non-Toxic | Mus musculus | |||||
13. | ALA4064834 | 30; GSK428 | Activity | 0 | ALA4012405 | Non-Toxic | Salmonella enterica subsp. enterica serovar Typhimurium | |||||
14. | ALA4064834 | 30; GSK428 | Activity | 0 | ALA4012404 | Non-Toxic | Salmonella enterica subsp. enterica serovar Typhimurium | |||||
15. | ALA4064834 | 30; GSK428 | INH | < | 20 | % | ALA4012403 | % | Homo sapiens | |||
16. | ALA4064834 | 30; GSK428 | INH | < | 20 | % | ALA4012402 | % | Homo sapiens | |||
17. | ALA4064834 | 30; GSK428 | INH | < | 20 | % | ALA4012401 | % | Homo sapiens | |||
18. | ALA4064834 | 30; GSK428 | INH | < | 20 | % | ALA4012400 | % | Homo sapiens | |||
19. | ALA4064834 | 30; GSK428 | INH | < | 20 | % | ALA4012399 | % | Homo sapiens | |||
20. | ALA4064834 | 30; GSK428 | Fu | = | 2.4 | % | ALA4012397 | Homo sapiens |