# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4066091 | 31b | INH | 0 | ALA4008499 | Not Active | % | Homo sapiens | ||||
2. | ALA4066091 | 31b | IC50 | = | 5.8 | nM | ALA4008498 | 8.24 | nM | Homo sapiens | ||
3. | ALA4066091 | 31b | Vd | = | 9.4 | L/Kg | ALA4008495 | L.kg-1 | Mus musculus | |||
4. | ALA4066091 | 31b | CL | = | 74 | ml/min.kg | ALA4008494 | mL.min-1.kg-1 | Mus musculus | |||
5. | ALA4066091 | 31b | AUC | = | 2252 | ug.hr/L | ALA4008493 | ng.hr.mL-1 | Mus musculus | |||
6. | ALA4066091 | 31b | t1/2 | = | 1.48 | hr | ALA4008492 | hr | Mus musculus | |||
7. | ALA4066091 | 31b | Drug metabolism | 0 | ALA4008480 | Metabolite_Detected | Homo sapiens | |||||
8. | ALA4066091 | 31b | Drug metabolism | 0 | ALA4008479 | Metabolite_Detected | Rattus norvegicus | |||||
9. | ALA4066091 | 31b | Stability | 0 | ALA4008476 | Stable | % | Homo sapiens | ||||
10. | ALA4066091 | 31b | Stability | 0 | ALA4008475 | Stable | % | |||||
11. | ALA4066091 | 31b | Stability | = | 87 | % | ALA4008474 | % | ||||
12. | ALA4066091 | 31b | Stability | = | 47 | % | ALA4008473 | % | ||||
13. | ALA4066091 | 31b | Stability | 0 | ALA4008472 | Stable | % | Rattus norvegicus | ||||
14. | ALA4066091 | 31b | Stability | 0 | ALA4008471 | Stable | % | Homo sapiens | ||||
15. | ALA4066091 | 31b | IC50 | = | 8.1 | nM | ALA4008461 | 8.09 | nM | Mus musculus | ||
16. | ALA4066091 | 31b | EC50 | = | 9.1 | nM | ALA4008462 | 8.04 | nM | Homo sapiens | ||
17. | ALA4066091 | 31b | IC50 | = | 7.8 | nM | ALA4008463 | 8.11 | nM | Homo sapiens |